⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14509591 | 0.70 | — | — | |
| SCHEMBL27700998 | 0.67 | — | — | |
| SCHEMBL3070228 | 0.65 | — | — | |
| SCHEMBL498733 | 0.59 | — | — | |
| SCHEMBL1945972 | 0.59 | TSHR (0.33) | — | |
| SCHEMBL465096 | 0.59 | — | — | |
| SCHEMBL14721642 | 0.59 | — | — | |
| SCHEMBL17729837 | 0.56 | — | — | |
| SCHEMBL2521037 | 0.56 | — | — | |
| SCHEMBL6359912 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2751106-A1 | SUBSTITUTED ANNELLATED PYRIMIDINE AND THE USE THEREOF | Bayer Intellectual Property GmbH (DE) | 2014-07-09 | — | — | EP | claimed |
| WO-2013030288-A1 | SUBSTITUTED ANNELLATED PYRIMIDINE AND THE USE THEREOF | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-03-07 | — | — | WO | claimed |
| US-8008358-B2 | having terminal pentafluorosulfuranyl group or terminal trifluoromethoxy group and also a polar end group; fully degradable substitutes for perfluorinated surfactants; paint, fire-extinguishing composition, lubricant, cleaner, deicer, hydrophobicising for textile finishing or glass treatment; emulsifier | MERCK PATENT GMBH (DE) | 2011-08-30 | — | — | US | claimed |
| EP-1833786-B1 | FLUOROSURFACTANTS | MERCK PATENT GMBH (DE) | 2010-02-17 | — | — | EP | claimed |
| US-20080149878-A1 | having terminal pentafluorosulfuranyl group or terminal trifluoromethoxy group and also a polar end group; fully degradable substitutes for perfluorinated surfactants; paint, fire-extinguishing composition, lubricant, cleaner, deicer, hydrophobicising for textile finishing or glass treatment; emulsifier | MERCK PATENT GMBH (DE) | 2008-06-26 | — | — | US | claimed |
| EP-1833786-A1 | FLUOROSURFACTANTS | Merck Patent GmbH (DE) | 2007-09-19 | — | — | EP | claimed |
| WO-2006072401-A1 | FLUOROSURFACTANTS | MERCK PATENT GMBH (DE) | 2006-07-13 | — | — | WO | claimed |
| EP-0558487-B1 | PIPERIDINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK AS (DK) | 1998-10-07 | — | — | EP | claimed |
| US-12152041-B2 | Macrocyclic fluorine substituted indole derivatives | THE BROAD INSTITUTE, INC. (US) | 2024-11-26 | — | — | US | disclosed |
| US-20240252661-A1 | PROTEIN-DRUG CONJUGATES COMPRISING CAMPTOTHECIN ANALOGS AND METHODS OF USE THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2024-08-01 | — | — | US | disclosed |
| EP-4406608-A2 | PROTEIN-DRUG CONJUGATES COMPRISING CAMPTOTHECIN ANALOGS AND METHODS OF USE THEREOF | Regeneron Pharmaceuticals, Inc. (US) | 2024-07-31 | — | — | EP | disclosed |
| US-20220281891-A1 | MACROCYCLIC FLUORINE SUBSTITUTED INDOLE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2022-09-08 | — | — | US | disclosed |
| US-20170275275-A1 | BENZENESULFONAMIDES USEFUL AS SODIUM CHANNEL INHIBITORS | PFIZER (US) | 2017-09-28 | — | — | US | disclosed |
| US-20170037010-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. | 2017-02-09 | — | — | US | disclosed |
| US-7385066-B2 | Thiophene sulfoximines, compositions thereof, and methods of treating complement-mediated diseases and conditions | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-06-10 | — | — | US | disclosed |
| EP-1833786-A1 | FLUOROSURFACTANTS | Merck Patent GmbH (DE) | 2007-09-19 | — | — | EP | disclosed |
| US-20070087346-A1 | Orthogonal gene switches | CILIBERTO GENNARO | 2007-04-19 | — | — | US | disclosed |
| US-20070066667-A1 | Novel thiophene sulfoximines, compositions thereof, and methods treating complement-mediated diseases and conditions | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-03-22 | — | — | US | disclosed |
| WO-2006072401-A1 | FLUOROSURFACTANTS | MERCK PATENT GMBH (DE) | 2006-07-13 | — | — | WO | disclosed |
| US-3860660-A | PERFLUORO ORGANIC HYDROPEROXIDES | ALLIED CHEM | 1975-01-14 | — | — | US | disclosed |