SCHEMBL17841968

SCHEMBL17841968

Brc1ccc2[nH]c3ccc4c5ccc6ccccc6c5ccc4c3c2c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK4 P11802 6/20 0.49
CCND1 P24385 6/20 0.49
GABRP O00591 2/20 0.48
GABRD O14764 2/20 0.48
GABRA1 P14867 2/20 0.48
GABRB1 P18505 2/20 0.48
GABRG2 P18507 2/20 0.48
GABRB3 P28472 2/20 0.48
GABRA5 P31644 2/20 0.48
GABRA3 P34903 2/20 0.48
GABRA2 P47869 2/20 0.48
GABRB2 P47870 2/20 0.48
GABRA4 P48169 2/20 0.48
GABRE P78334 2/20 0.48
GABRA6 Q16445 2/20 0.48
GABRG1 Q8N1C3 2/20 0.48
GABRG3 Q99928 2/20 0.48
GABRQ Q9UN88 2/20 0.48
CCNB2 O95067 3/20 0.46
CDK1 P06493 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10044741 0.92 CDK4 (0.53) CDK4CCND1GABRPGABRDGABRA1
SCHEMBL2627625 0.86 CDK4 (0.51) CDK4CCND1GABRPGABRDGABRA1
SCHEMBL16536029 0.85 CDK4 (0.66) CDK4CCND1GABRPGABRDGABRA1
SCHEMBL15055536 0.85 CHUK (0.50) CDK4CCND1GABRPGABRDGABRA1
SCHEMBL30849130 0.84 CDK4 (0.51) CDK4CCND1GABRPGABRDGABRA1
SCHEMBL30221171 0.84 CDK4 (0.51) CDK4CCND1GABRPGABRDGABRA1
SCHEMBL31622 0.84 CDK4 (0.51) CDK4CCND1GABRPGABRDGABRA1
SCHEMBL29792981 0.83 CDK4 (0.62) CDK4CCND1GABRPGABRDGABRA1
SCHEMBL17841956 0.83 CDK4 (0.62) CDK4CCND1GABRPGABRDGABRA1
SCHEMBL15822869 0.83 CDK4 (0.62) CDK4CCND1GABRPGABRDGABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016099037-A2 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2016-06-23 WO disclosed
WO-2016099037-A2 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2016-06-23 WO disclosed