Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7024101 | 0.79 | HTT (0.48) | HTTCES2CES1PKMSMN1; SMN2 | |
| SCHEMBL14517812 | 0.74 | HTT (0.39) | HTTCES2CES1PKMSMN1; SMN2 | |
| SCHEMBL11122131 | 0.74 | MEN1 (0.44) | HTTCES2CES1PKMSMN1; SMN2 | |
| SCHEMBL1481978 | 0.74 | PTPN1 (0.44) | HTTCES2CES1PKMSMN1; SMN2 | |
| SCHEMBL330842 | 0.72 | HTT (0.43) | HTTCES2CES1PKMSMN1; SMN2 | |
| SCHEMBL8827233 | 0.72 | HTT (0.38) | HTTCES2CES1PKMSMN1; SMN2 | |
| SCHEMBL13670601 | 0.72 | HTT (0.43) | HTTCES2CES1PKMSMN1; SMN2 | |
| SCHEMBL23692883 | 0.70 | FASN (0.42) | HTTCES2CES1PKMSMN1; SMN2 | |
| SCHEMBL28731623 | 0.70 | HTT (0.37) | HTTCES2CES1PKMSMN1; SMN2 | |
| SCHEMBL25992037 | 0.69 | MCL1 (0.39) | HTTCES2CES1PKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110124891-A1 | ALPHA-PENTAFLUOROSULFANYL ALDEHYDES, KETONES AND ACIDS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | 2011-05-26 | — | — | US | disclosed |
| WO-2009026191-A1 | ALPHA-PENTAFLUOROSUFANYL ALDEHYDES, KETONES AND ACIDS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2009-02-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124891-A1 | ALPHA-PENTAFLUOROSULFANYL ALDEHYDES, KETONES AND ACIDS | CBR1, CBR3, AKR1C3 | HTT 2390/4885CES2 751/4885CES1 549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.