Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Succinimide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 8/20 | 0.55 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.50 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.50 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.37 |
| ▸ | ITGAV | P06756 | 2/20 | 0.37 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.37 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.37 |
| ▸ | ITGAL | P20701 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL17336167 | 0.91 | CRBN (0.59) | CRBNGLRA1SLC6A9OR51E2DDB1 | |
| Succinimide SCHEMBL16500285 | 0.84 | CRBN (0.48) | CRBNGLRA1SLC6A9OR51E2DDB1 | |
| Succinic Acid SCHEMBL27747025 | 0.82 | CRBN (0.58) | CRBNOR51E2ITGB3ITGB1ITGAV | |
| Succinic Acid SCHEMBL436244 | 0.82 | CRBN (0.58) | CRBNOR51E2ITGB3ITGB1ITGAV | |
| Succinimide SCHEMBL9241351 | 0.82 | CRBN (0.58) | CRBNDDB1ITGB3ITGB1ITGAV | |
| Succinimide SCHEMBL27595841 | 0.81 | CRBN (0.65) | CRBNDDB1ITGB3ITGB1ITGAV | |
| Succinimide SCHEMBL6717091 | 0.81 | CRBN (0.73) | CRBNDDB1ITGB3ITGB1ITGAV | |
| Succinimide SCHEMBL6036901 | 0.81 | CRBN (0.73) | CRBNDDB1ITGB3ITGB1ITGAV | |
| Succinimide SCHEMBL434236 | 0.81 | CRBN (0.73) | CRBNDDB1ITGB3ITGB1ITGAV | |
| Succinimide SCHEMBL2221415 | 0.80 | CRBN (0.55) | CRBNDDB1ITGB3ITGB1ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115887737-A | Biodegradable tissue patch in organism and preparation method thereof | 诺一迈尔(苏州)生命科技有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-107108496-B | Multifunctional hydroxyphthalimide monomer compound | 帝斯曼知识产权资产管理有限公司 | 2021-05-28 | — | — | CN | disclosed |
| EP-3233796-B1 | POLYFUNCTIONAL HYDROPHTHALIMIDE MONOMER COMPOUNDS | DSM IP ASSETS BV (NL) | 2020-08-26 | — | — | EP | disclosed |
| EP-3233795-B1 | ALKYD RESIN COMPOSITIONS OF POLYFUNCTIONAL HYDROPHTHALIMIDE MONOMER COMPOUNDS | DSM IP ASSETS BV (NL) | 2020-05-13 | — | — | EP | disclosed |
| CN-107108889-B | Alkyd resin composition of multifunctional hydroxyphthalimide monomer compound | 帝斯曼知识产权资产管理有限公司 | 2020-04-21 | — | — | CN | disclosed |
| US-10189783-B2 | Polyfunctional compounds | DSM IP ASSETS B.V. (NL) | 2019-01-29 | — | — | US | disclosed |
| US-10167365-B2 | Polymer and composition | DSM IP ASSETS B.V. (NL) | 2019-01-01 | — | — | US | disclosed |
| US-10066053-B2 | Alkyd resin compositions | DSM IP ASSETS B.V. (NL) | 2018-09-04 | — | — | US | disclosed |
| US-20170355672-A1 | POLYFUNCTIONAL COMPOUNDS | COVESTRO (NETHERLANDS) B.V. (NL) | 2017-12-14 | — | — | US | disclosed |
| EP-3055340-B1 | POLYMER AND COMPOSITION | DSM IP ASSETS BV (NL) | 2017-11-22 | — | — | EP | disclosed |
| US-20170327636-A1 | ALKYD RESIN COMPOSITIONS | COVESTRO (NETHERLANDS) B.V. (NL) | 2017-11-16 | — | — | US | disclosed |
| EP-3233795-A1 | ALKYD RESIN COMPOSITIONS OF POLYFUNCTIONAL HYDROPHTHALIMIDE MONOMER COMPOUNDS | DSM IP Assets B.V. (NL) | 2017-10-25 | — | — | EP | disclosed |
| EP-3233796-A1 | POLYFUNCTIONAL HYDROPHTHALIMIDE MONOMER COMPOUNDS | DSM IP Assets B.V. (NL) | 2017-10-25 | — | — | EP | disclosed |
| CN-107108889-A | The alkyd resin composition of multifunctional hydroxyphthalimide monomeric compound | 帝斯曼知识产权资产管理有限公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-107108496-A | multifunctional hydroxyphthalimide monomer compound | 帝斯曼知识产权资产管理有限公司 | 2017-08-29 | — | — | CN | disclosed |
| US-20160237213-A1 | POLYMER AND COMPOSITION | COVESTRO (NETHERLANDS) B.V. (NL) | 2016-08-18 | — | — | US | disclosed |
| WO-2016097403-A1 | POLYFUNCTIONAL HYDROPHTHALIMIDE MONOMER COMPOUNDS | DSM IP ASSETS B.V. (NL) | 2016-06-23 | — | — | WO | disclosed |
| WO-2016097404-A1 | ALKYD RESIN COMPOSITIONS OF POLYFUNCTIONAL HYDROPHTHALIMIDE MONOMER COMPOUNDS | DSM IP ASSETS B.V. (NL) | 2016-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170355672-A1 | POLYFUNCTIONAL COMPOUNDS | H1-3, H1-0, H1-2 | CRBN 267/4885GLRA1 1040/4885SLC6A9 4561/4885 |
| US-10189783-B2 | Polyfunctional compounds | H1-3, H1-0, H1-2 | CRBN 267/4885GLRA1 1040/4885SLC6A9 4561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.