Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | CA6 | P23280 | 1/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.60 |
| ▸ | CA7 | P43166 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12209941 | 0.94 | POLB (0.57) | POLBCA1CA2CA6OPRK1 | |
| SCHEMBL31195399 | 0.81 | CA1 (0.61) | POLBCA1CA2CA6OPRK1 | |
| SCHEMBL8262169 | 0.81 | CA1 (0.61) | POLBCA1CA2CA6OPRK1 | |
| SCHEMBL1030597 | 0.81 | CA1 (0.66) | POLBCA1CA2CA6OPRK1 | |
| SCHEMBL8358594 | 0.81 | CA1 (0.61) | POLBCA1CA2CA6OPRK1 | |
| SCHEMBL25845301 | 0.81 | CA1 (0.61) | POLBCA1CA2CA6OPRK1 | |
| SCHEMBL5362725 | 0.80 | POLB (0.68) | POLBCA1CA2CA6OPRK1 | |
| Hydrochloric Acid SCHEMBL3544398 | 0.79 | CA1 (0.64) | POLBCA1CA2CA6OPRK1 | |
| SCHEMBL15683644 | 0.79 | CA1 (0.59) | POLBCA1CA2CA6OPRK1 | |
| SCHEMBL10053487 | 0.79 | POLB (0.62) | POLBCA1CA2CA6OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233849-A1 | HETEROARYLALKYLENE ARYL SULTAM DERIVATIVES AS RORc MODULATORS | F. Hoffmann-La Roche AG (CH) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016096936-A1 | HETEROARYLALKYLENE ARYL SULTAM DERIVATIVES AS RORc MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2016-06-23 | — | — | WO | disclosed |