Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17845085 | 0.86 | ESR1 (0.38) | ESR1TNK2 | |
| SCHEMBL17845119 | 0.80 | ESR1 (0.38) | ESR1 | |
| SCHEMBL21780917 | 0.74 | ESR1 (0.48) | ESR1 | |
| SCHEMBL17845111 | 0.72 | ESR1 (0.37) | ESR1 | |
| SCHEMBL17858145 | 0.72 | ESR1 (0.48) | ESR1 | |
| SCHEMBL17845094 | 0.70 | PTGS1 (0.38) | TNK2 | |
| SCHEMBL17845123 | 0.69 | ESR1 (0.46) | ESR1 | |
| SCHEMBL17845162 | 0.69 | ESR1 (0.46) | ESR1 | |
| SCHEMBL17845161 | 0.69 | ESR1 (0.46) | ESR1 | |
| SCHEMBL17845087 | 0.68 | TNK2 (0.39) | TNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233828-A1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | F. Hoffmann-La Roche AG (CH) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016097071-A1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | F. HOFFMANN-LA ROCHE AG (CH) | 2016-06-23 | — | — | WO | disclosed |