SCHEMBL17845352

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31122009	1.00	GFER (0.63)	GFERSMN1; SMN2PARGHDAC3HDAC4
	SCHEMBL31591380	0.81	SMN1; SMN2 (0.71)	GFERSMN1; SMN2HDAC3HDAC4HDAC1
	SCHEMBL1818147	0.81	SMN1; SMN2 (0.71)	GFERSMN1; SMN2HDAC3HDAC4HDAC1
	SCHEMBL1128542	0.76	GFER (0.63)	GFERSMN1; SMN2HDAC3HDAC4HDAC1
	SCHEMBL19785877	0.76	PARG (0.45)	PARG
	SCHEMBL26812415	0.73	GFER (0.60)	GFERSMN1; SMN2HDAC3HDAC4HDAC1
	SCHEMBL30664965	0.72	CA1 (0.61)	GFERSMN1; SMN2HDAC3HDAC4HDAC1
	SCHEMBL4230983	0.72	CA1 (0.61)	GFERSMN1; SMN2HDAC3HDAC4HDAC1
	SCHEMBL27947100	0.72	SMN1; SMN2 (0.63)	GFERSMN1; SMN2HDAC3HDAC4HDAC1
	SCHEMBL1806454	0.72	GFER (0.59)	GFERSMN1; SMN2HDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.