Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 20/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17847940 | 0.88 | MAPK1 (1.00) | MAPK1 | |
| SCHEMBL17847942 | 0.88 | MAPK1 (1.00) | MAPK1 | |
| SCHEMBL19349163 | 0.85 | MAPK1 (0.75) | MAPK1 | |
| SCHEMBL17848039 | 0.85 | MAPK1 (0.75) | MAPK1 | |
| SCHEMBL17848014 | 0.85 | MAPK1 (0.83) | MAPK1 | |
| SCHEMBL17848013 | 0.85 | MAPK1 (0.83) | MAPK1 | |
| SCHEMBL17847976 | 0.80 | MAPK1 (0.72) | MAPK1 | |
| SCHEMBL17847973 | 0.80 | MAPK1 (0.72) | MAPK1 | |
| SCHEMBL17847943 | 0.80 | MAPK1 (0.75) | MAPK1 | |
| SCHEMBL17846233 | 0.80 | MAPK1 (0.75) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016095089-A1 | ERK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-06-23 | — | — | WO | disclosed |