Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 14/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 14/20 | 0.70 |
| ▸ | NPC1 | O15118 | 11/20 | 0.70 |
| ▸ | RAB9A | P51151 | 8/20 | 0.70 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.70 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.70 |
| ▸ | ECE2 | P0DPD6 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | CD74 | P04233 | 1/20 | 0.58 |
| ▸ | MIF | P14174 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1784646 | 1.00 | MEN1 (0.70) | MEN1KMT2ANPC1RAB9AAGTR1 | |
| SCHEMBL16970988 | 0.82 | MEN1 (0.70) | MEN1KMT2ANPC1RAB9AAGTR1 | |
| SCHEMBL1785244 | 0.82 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9AAGTR1 | |
| SCHEMBL16971022 | 0.82 | KMT2A (1.00) | MEN1KMT2ANPC1RAB9AAGTR1 | |
| SCHEMBL16971024 | 0.82 | KMT2A (1.00) | MEN1KMT2ANPC1RAB9AAGTR1 | |
| SCHEMBL1785243 | 0.82 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9AAGTR1 | |
| SCHEMBL16970987 | 0.82 | MEN1 (0.70) | MEN1KMT2ANPC1RAB9AAGTR1 | |
| SCHEMBL16971009 | 0.79 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9AAGTR1 | |
| SCHEMBL16971008 | 0.79 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9AAGTR1 | |
| SCHEMBL28157024 | 0.79 | KMT2A (0.65) | MEN1KMT2ANPC1RAB9AAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110201719-B | Pharmaceutical sewage treatment method | 南京科技职业学院 | 2020-04-21 | — | — | CN | claimed |
| CN-110201719-A | A kind of pharmacy sewage administering method | 南京科技职业学院 | 2019-09-06 | — | — | CN | claimed |
| CN-110201719-B | Pharmaceutical sewage treatment method | 南京科技职业学院 | 2020-04-21 | — | — | CN | disclosed |
| CN-110201719-A | A kind of pharmacy sewage administering method | 南京科技职业学院 | 2019-09-06 | — | — | CN | disclosed |
| EP-3147280-B1 | ANTI-ANGIOGENIC COMPOUND | UNIV COLLEGE DUBLIN NAT UNIV IRELAND DUBLIN (IE) | 2018-03-07 | — | — | EP | disclosed |
| US-9815788-B2 | Anti-angiogenic compounds | THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN (IE) | 2017-11-14 | — | — | US | disclosed |
| EP-3147280-A1 | ANTI-ANGIOGENIC COMPOUND | University College Dublin, National University of Ireland, Dublin (IE) | 2017-03-29 | — | — | EP | disclosed |
| US-20170050930-A1 | ANTI-ANGIOGENIC COMPOUNDS | UNIVERSITY COLLEGE DUBLIN NATIONAL UNIVERSITY OF IRELAND, DUBLIN (IE) | 2017-02-23 | — | — | US | disclosed |
| EP-2877454-B1 | ANTI-ANGIOGENIC 2-STYRYL-QUINOLINE COMPOUNDS | UNIV DUBLIN (IE) | 2016-11-02 | — | — | EP | disclosed |
| US-9388138-B2 | Anti-angiogenic compounds | UNIVERSITY COLLEGE DUBLIN NATIONAL UNIVERSITY OF IRELAND, DUBLIN (IE) | 2016-07-12 | — | — | US | disclosed |
| US-20150218100-A1 | ANTI-ANGIOGENIC COMPOUNDS | UNIVERSITY COLLEGE DUBLIN NATIONAL UNIVERSITY OF IRELAND, DUBLIN (IE) | 2015-08-06 | — | — | US | disclosed |
| US-9012899-B2 | Electroluminescent metal complexes with nucleophilic carbene ligands | BASF SE (DE) | 2015-04-21 | — | — | US | disclosed |
| US-20130292660-A1 | ELECTROLUMINESCENT METAL COMPLEXES WITH NUCLEOPHILIC CARBENE LIGANDS | BASF SE (DE) | 2013-11-07 | — | — | US | disclosed |
| US-8492749-B2 | Electroluminescent metal complexes with nucleophilic carbene ligands | BASF SE (DE) | 2013-07-23 | — | — | US | disclosed |
| US-20110114922-A1 | Electroluminescent Metal Complexes with Nucleophilic Carbene Ligands | UDC IRELAND LIMITED (IE) | 2011-05-19 | — | — | US | disclosed |
| EP-2080796-A1 | Electroluminescent metal complexes with nucleophilic carbene ligands | Ciba Holding Inc. (CH) | 2009-07-22 | — | — | EP | disclosed |
| EP-1841834-A1 | ELECTROLUMINESCENT METAL COMPLEXES WITH NUCLEOPHILIC CARBENE LIGANDS | Ciba Specialty Chemicals Holding Inc. (CH) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006067074-A1 | ELECTROLUMINESCENT METAL COMPLEXES WITH NUCLEOPHILIC CARBENE LIGANDS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170050930-A1 | ANTI-ANGIOGENIC COMPOUNDS | VEGFA, FLT4, VHL | MEN1 4178/4885KMT2A 3493/4885NPC1 2305/4885 |
| US-20150218100-A1 | ANTI-ANGIOGENIC COMPOUNDS | VEGFA, FLT4, VHL | MEN1 4178/4885KMT2A 3493/4885NPC1 2305/4885 |
| US-20110114922-A1 | Electroluminescent Metal Complexes with Nucleophilic Carbene Ligands | OCIAD1, OCIAD2, C1S | MEN1 2019/4885KMT2A 3572/4885NPC1 4207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.