Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17846802 | 0.82 | HCRTR1 (1.00) | HCRTR2HCRTR1 | |
| SCHEMBL17846790 | 0.81 | HCRTR1 (0.68) | HCRTR2HCRTR1 | |
| SCHEMBL17846792 | 0.70 | HCRTR1 (0.67) | HCRTR2HCRTR1 | |
| SCHEMBL17846752 | 0.70 | HCRTR1 (1.00) | HCRTR2HCRTR1 | |
| SCHEMBL17846729 | 0.70 | HCRTR1 (1.00) | HCRTR2HCRTR1 | |
| SCHEMBL17846706 | 0.70 | HCRTR2 (1.00) | HCRTR2HCRTR1 | |
| SCHEMBL17846782 | 0.69 | HCRTR1 (0.67) | HCRTR2HCRTR1 | |
| SCHEMBL19689855 | 0.68 | HCRTR1 (1.00) | HCRTR2HCRTR1 | |
| SCHEMBL17846756 | 0.67 | HCRTR1 (1.00) | HCRTR2HCRTR1 | |
| SCHEMBL17846773 | 0.67 | HCRTR2 (1.00) | HCRTR2HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100161-A1 | ETHYLDIAMINE OREXIN RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME CORP. (US) | 2016-06-23 | — | — | WO | claimed |