SCHEMBL1784729

SCHEMBL1784729

CC(C)(CCCOC(=O)c1ccccc1)COC(=O)c1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.64
MAPK1 P28482 2/20 0.57
HIF1A Q16665 1/20 0.57
LMNA P02545 2/20 0.56
SLC6A3 Q01959 2/20 0.51
SCN1A P35498 2/20 0.51
SCN2A Q99250 2/20 0.51
SCN3A Q9NY46 2/20 0.51
CYP2D6 P10635 2/20 0.51
HTR1A P08908 1/20 0.51
SCN5A Q14524 1/20 0.51
ALDH1A1 P00352 3/20 0.48
KMT2A Q03164 2/20 0.48
TSHR P16473 3/20 0.45
SLC6A2 P23975 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.44
ADRB2 P07550 1/20 0.44
ADRB1 P08588 1/20 0.44
ADRB3 P13945 1/20 0.44
ESR1 P03372 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16045397 0.90 TDP1 (0.51) TDP1MAPK1HIF1ALMNASLC6A3
SCHEMBL16045395 0.90 TDP1 (0.55) TDP1MAPK1HIF1ALMNASLC6A3
SCHEMBL3960287 0.88 TDP1 (0.64) TDP1MAPK1HIF1ALMNASLC6A3
SCHEMBL3953881 0.88 MAPK1 (0.57) TDP1MAPK1HIF1ALMNASLC6A3
SCHEMBL21113688 0.85 TDP1 (0.70) TDP1MAPK1HIF1ALMNASLC6A3
SCHEMBL15253791 0.85 TDP1 (0.47) TDP1MAPK1HIF1ALMNASLC6A3
SCHEMBL16044284 0.85 TDP1 (0.53) TDP1MAPK1HIF1ALMNASLC6A3
SCHEMBL20512188 0.85 TDP1 (0.53) TDP1MAPK1HIF1ALMNASLC6A3
SCHEMBL204567 0.85 MAPK1 (0.71) TDP1MAPK1HIF1ALMNASLC6A3
SCHEMBL21561547 0.84 TDP1 (0.68) TDP1MAPK1HIF1ALMNASLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115975075-B Catalyst component for olefin polymerization, catalyst and application 中国石油化工股份有限公司 2024-09-17 CN claimed
CN-115975075-A Catalyst component for olefin polymerization, catalyst and application 中国石油化工股份有限公司 2023-04-18 CN claimed
EP-3059264-B1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, PREPARATION METHOD THEREOF, AND CATALYST COMPRISING SAME CHINA PETROLEUM & CHEM CORP (CN) 2018-12-26 EP claimed
EP-1472293-B1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2017-04-26 EP claimed
US-20160264694-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, PREPARATION METHOD THEREOF, AND CATALYST COMPRISING SAME CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2016-09-15 US claimed
EP-3059264-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, PREPARATION METHOD THEREOF, AND CATALYST COMPRISING SAME China Petroleum&Chemical Corporation (CN) 2016-08-24 EP claimed
US-7388061-B2 Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-06-17 US claimed
US-20050239636-A1 Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-10-27 US claimed
US-20230391902-A1 MAGNESIUM-BASED SOLID AND CATALYST COMPONENT HAVING MULTIMODAL PORE DISTRIBUTION, AND PREPARATION METHODS THEREFOR CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2023-12-07 US disclosed
EP-4230662-A1 MAGNESIUM-BASED SOLID AND CATALYST COMPONENT HAVING MULTIMODAL PORE DISTRIBUTION, AND PREPARATION METHODS THEREFOR CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2023-08-23 EP disclosed
CN-115975075-A Catalyst component for olefin polymerization, catalyst and application 中国石油化工股份有限公司 2023-04-18 CN disclosed
CN-114716591-A Catalyst component for propylene polymerization, preparation method and application thereof 任丘市利和科技发展有限公司 2022-07-08 CN disclosed
WO-2022078492-A1 MAGNESIUM-BASED SOLID AND CATALYST COMPONENT HAVING MULTIMODAL PORE DISTRIBUTION, AND PREPARATION METHODS THEREFOR 中国石油化工股份有限公司 2022-04-21 WO disclosed
CN-109694427-B Polypropylene, preparation method and application thereof 中国石油化工股份有限公司 2022-03-15 CN disclosed
US-20050119427-A1 Catalyst component and catalyst for olefin polymerization as well as use thereof BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-06-02 US disclosed
US-20050096389-A1 Polyol ester compounds useful in preparation of a catalyst for olefins polymerization, process for preparing the same and use thereof CHINA PETROLEUM & CHEMICAL (CN) 2005-05-05 US disclosed
CN-1552742-A Catalyst component for olefin polymerization reaction and catalyst 中国石油化工股份有限公司 2004-12-08 CN disclosed
EP-1478617-A1 POLYOL ESTER COMPOUNDS USEFUL IN PREPARATION OF A CATALYST FOR OLEFINS POLYMERIZATION, PROCESS FOR PREPARING THE SAME AND USE THEREOF China Petroleum & Chemical Corporation (CN) 2004-11-24 EP disclosed
CN-1446197-A Oxygenated esters of 4-iodo phenylamino benzhydroxamic acids WARNER LAMBERT CO (US) 2003-10-01 CN disclosed
WO-2003068723-A1 POLYOL ESTER COMPOUNDS USEFUL IN PREPARATION OF A CATALYST FOR OLEFINS POLYMERIZATION, PROCESS FOR PREPARING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2003-08-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050096389-A1 Polyol ester compounds useful in preparation of a catalyst for olefins polymerization, process for preparing the same and use thereof CBR3, CBR1, OXER1 TDP1 4722/4885MAPK1 2038/4885HIF1A 2560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.