Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 2/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19714935 | 0.95 | SLC29A1 (0.46) | SLC29A1CDK1CCNB2CCNB1CCNB3 | |
| SCHEMBL17847272 | 0.93 | SLC29A1 (0.41) | SLC29A1CDK1CCNB2CCNB1CCNB3 | |
| SCHEMBL17847680 | 0.91 | CCNB2 (0.43) | SLC29A1CDK1CCNB2CCNB1CCNB3 | |
| SCHEMBL17847266 | 0.91 | SLC29A1 (0.40) | SLC29A1CDK1CCNB2CCNB1CCNB3 | |
| SCHEMBL19714879 | 0.87 | SLC29A1 (0.44) | SLC29A1CDK1CCNB2CCNB1CCNB3 | |
| SCHEMBL17847685 | 0.86 | NPC1 (0.41) | SLC29A1CDK1CCNB2CCNB1CCNB3 | |
| SCHEMBL17847688 | 0.86 | NPC1 (0.41) | SLC29A1CDK1CCNB2CCNB1CCNB3 | |
| SCHEMBL19714872 | 0.86 | SLC29A1 (0.42) | SLC29A1CDK1CCNB2CCNB1CCNB3 | |
| SCHEMBL19715019 | 0.85 | SLC29A1 (0.42) | SLC29A1CDK1CCNB2CCNB1CCNB3 | |
| SCHEMBL17847304 | 0.84 | SLC29A1 (0.43) | SLC29A1CDK1CCNB2CCNB1CCNB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233861-A1 | 6,8-DISUBSTITUTED-9-(HETEROCYCLYL)PURINES, COMPOSITIONS CONTAINING THESE DERIVATIVES AND THEIR USE IN COSMETIC AND MEDICINAL APPLICATIONS | Ustav Experimentalni Botaniky Av CR, V.V.I. (CZ) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016095880-A1 | 6,8-DISUBSTITUTED-9-(HETEROCYCLYL)PURINES, COMPOSITIONS CONTAINING THESE DERIVATIVES AND THEIR USE IN COSMETIC AND MEDICINAL APPLICATIONS | USTAV EXPERIMENTALNI BOTANIKY AV CR, V.V.I. (CZ) | 2016-06-23 | — | — | WO | disclosed |