Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK3 | P27361 | 18/20 | 0.64 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17847674 | 0.90 | MAPK3 (0.78) | MAPK3PTK2MAPK1 | |
| SCHEMBL17847689 | 0.79 | MAPK3 (0.69) | MAPK3MAPK1 | |
| SCHEMBL15938379 | 0.78 | MAPK3 (1.00) | MAPK3MAPK1 | |
| SCHEMBL17847675 | 0.73 | MAPK3 (0.58) | MAPK3MAPK1 | |
| SCHEMBL18256232 | 0.73 | MAPK3 (0.82) | MAPK3MAPK1 | |
| SCHEMBL15938494 | 0.72 | MAPK3 (0.73) | MAPK3PTK2 | |
| SCHEMBL18469802 | 0.71 | MAPK3 (0.69) | MAPK3PTK2 | |
| SCHEMBL17847673 | 0.71 | MAPK3 (0.65) | MAPK3MAPK1 | |
| SCHEMBL15937930 | 0.71 | MAPK3 (1.00) | MAPK3MAPK1 | |
| SCHEMBL18470437 | 0.70 | MAPK3 (0.66) | MAPK3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100452-A2 | HETEROARYL COMPOUNDS AND USES THEREOF | CELGENE AVILOMICS RESEARCH, INC. (US) | 2016-06-23 | — | — | WO | disclosed |