Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19806732 | 0.87 | KMT2A (0.53) | KMT2AASAH1SMN1; SMN2MAOBL3MBTL1 | |
| SCHEMBL19651377 | 0.83 | KMT2A (0.57) | KMT2AASAH1SMN1; SMN2L3MBTL1NPC1 | |
| SCHEMBL4770316 | 0.82 | KMT2A (0.78) | KMT2AASAH1SMN1; SMN2L3MBTL1NPC1 | |
| SCHEMBL6937444 | 0.78 | KMT2A (0.68) | KMT2ASMN1; SMN2MEN1L3MBTL1KLK7 | |
| SCHEMBL17971120 | 0.78 | APP (0.40) | KMT2ASMN1; SMN2MEN1CA2 | |
| SCHEMBL17857804 | 0.77 | KMT2A (0.58) | KMT2AASAH1SMN1; SMN2MAOBMAOA | |
| SCHEMBL15763945 | 0.76 | KMT2A (0.42) | KMT2ASMN1; SMN2MEN1MAOBL3MBTL1 | |
| SCHEMBL18118880 | 0.75 | KMT2A (0.41) | KMT2AASAH1SMN1; SMN2MEN1L3MBTL1 | |
| SCHEMBL31225539 | 0.75 | KMT2A (0.51) | KMT2ASMN1; SMN2MEN1RAB9AKLK7 | |
| SCHEMBL19599396 | 0.75 | KMT2A (0.59) | KMT2AASAH1SMN1; SMN2MAOBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3234067-B1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2018-08-22 | — | — | EP | disclosed |
| US-20180022996-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| US-20180022996-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| US-20180022996-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| US-20170369784-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2017-12-28 | — | — | US | disclosed |
| EP-3234067-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | Merck Patent GmbH (DE) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016107664-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016096082-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2016-06-23 | — | — | WO | disclosed |
| WO-2016096081-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2016-06-23 | — | — | WO | disclosed |
| WO-2016096082-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2016-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170369784-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MTX1, S100A11, MCRS1 | KMT2A 3390/4885ASAH1 4725/4885SMN1; SMN2 2765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.