Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | DTYMK | P23919 | 1/20 | 0.46 |
| ▸ | F13A1 | P00488 | 3/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14059359 | 0.98 | MAPT (0.50) | MAPTRXFP1CYP1A2DTYMKF13A1 | |
| SCHEMBL30917811 | 0.94 | CYP1A2 (0.53) | MAPTRXFP1CYP1A2DTYMKFFAR1 | |
| SCHEMBL16840963 | 0.94 | CYP1A2 (0.53) | MAPTRXFP1CYP1A2DTYMKFFAR1 | |
| SCHEMBL9247568 | 0.87 | FFAR1 (0.55) | FFAR1FFAR4 | |
| SCHEMBL30816271 | 0.87 | FFAR1 (0.55) | FFAR1FFAR4 | |
| SCHEMBL10277036 | 0.85 | MAPT (0.58) | MAPTRXFP1CYP1A2F13A1TBXAS1 | |
| SCHEMBL14555727 | 0.85 | IGF1R (0.40) | HDAC1HDAC8 | |
| SCHEMBL29331986 | 0.85 | IGF1R (0.40) | HDAC1HDAC8 | |
| SCHEMBL30428461 | 0.83 | MAPT (0.55) | MAPTRXFP1CYP1A2F13A1TBXAS1 | |
| SCHEMBL16582468 | 0.82 | PDE3B (0.46) | HDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107109221-B | Bimesogenic compounds and mesogenic media | 默克专利股份有限公司 | 2021-03-12 | — | — | CN | disclosed |
| US-10392561-B2 | Bimesogenic compounds and mesogenic media | MERCK PATENT GMBH (DE) | 2019-08-27 | — | — | US | disclosed |
| US-10392561-B2 | Bimesogenic compounds and mesogenic media | MERCK PATENT GMBH (DE) | 2019-08-27 | — | — | US | disclosed |
| EP-3234065-B1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2018-09-26 | — | — | EP | disclosed |
| US-20170327741-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2017-11-16 | — | — | US | disclosed |
| US-20170327741-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2017-11-16 | — | — | US | disclosed |
| US-20170327741-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2017-11-16 | — | — | US | disclosed |
| EP-3234065-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | Merck Patent GmbH (DE) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016096112-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2016-06-23 | — | — | WO | disclosed |
| WO-2016096112-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2016-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170327741-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | SP1, FOXM1, S100A11 | MAPT 1228/4885RXFP1 368/4885CYP1A2 2116/4885 |
| US-10392561-B2 | Bimesogenic compounds and mesogenic media | SP1, FOXM1, S100A11 | MAPT 1228/4885RXFP1 368/4885CYP1A2 2116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.