Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.34 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | CHUK | O15111 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17848120 | 0.84 | IKBKE (0.41) | GSK3BFFAR1MAPK1MAPTNPSR1 | |
| SCHEMBL17848139 | 0.81 | GSK3B (0.47) | GSK3BFFAR1MAPK1NTRK1FLT3 | |
| SCHEMBL17848094 | 0.79 | NTRK1 (0.39) | GSK3BNTRK1CHUKDYRK1A | |
| SCHEMBL17848123 | 0.73 | FFAR1 (0.36) | FFAR1MAPTNPSR1GPR34FFAR4 | |
| SCHEMBL17848104 | 0.66 | IKBKE (0.43) | GSK3BFFAR1MAPK1MAPTNPSR1 | |
| SCHEMBL17859118 | 0.65 | FFAR1 (0.39) | FFAR1MAPTFFAR4 | |
| SCHEMBL3510459 | 0.63 | NTRK1 (0.77) | NTRK1 | |
| SCHEMBL17859182 | 0.62 | F9 (0.38) | FFAR1MAPK1MAPTNPSR1NOD2 | |
| SCHEMBL6487527 | 0.61 | GSK3B (0.86) | GSK3B | |
| SCHEMBL1461692 | 0.61 | GSK3B (0.84) | GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233840-A1 | HETEROCYCLIC DERIVATIVES MODULATING ACTIVITY OF CERTAIN PROTEIN KINASES | Eudendron S.r.l. (IT) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016096709-A1 | HETEROCYCLIC DERIVATIVES MODULATING ACTIVITY OF CERTAIN PROTEIN KINASES | EUDENDRON S.R.L. (IT) | 2016-06-23 | — | — | WO | disclosed |