SCHEMBL17848563

SCHEMBL17848563

C=C(C(=O)OCCCCCCCCCC)C(CCCCCC)CCCCCCCC

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.61
NAAA Q02083 1/20 0.47
RAD52 P43351 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
CA2 P00918 2/20 0.44
EPHX1 P07099 1/20 0.44
ZDHHC7 Q9NXF8 1/20 0.42
HCAR2 Q8TDS4 1/20 0.41
CA1 P00915 1/20 0.41
FAAH O00519 1/20 0.40
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
GRIK1 P39086 1/20 0.40
GRIK2 Q13002 1/20 0.40
ACHE P22303 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL689149 1.00 TSHR (0.61) TSHRNAAARAD52NPSR1CA2
Methacrylic Acid SCHEMBL11248118 0.89 TSHR (0.57) TSHRNAAARAD52NPSR1CA2
SCHEMBL11741714 0.88 TSHR (0.50) TSHRNAAARAD52NPSR1CA2
SCHEMBL7637382 0.88 TSHR (0.50) TSHRNAAACA2ZDHHC7CA1
SCHEMBL11139716 0.88 TSHR (0.62) TSHRNAAARAD52NPSR1CA2
SCHEMBL27471248 0.85 TSHR (0.59) TSHRNAAARAD52NPSR1EPHX1
SCHEMBL27457194 0.85 TSHR (0.59) TSHRNAAARAD52NPSR1EPHX1
SCHEMBL27480727 0.85 TSHR (0.59) TSHRNAAARAD52NPSR1EPHX1
SCHEMBL5432582 0.85 TSHR (0.59) TSHRNAAARAD52NPSR1EPHX1
SCHEMBL21638809 0.85 TSHR (0.59) TSHRNAAARAD52NPSR1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10703840-B2 Method for the preparation of copolymers of alkyl methacrylates and maleic anhydride EVONIK OPERATIONS GMBH (DE) 2020-07-07 US disclosed
EP-3233946-B1 METHOD FOR THE PREPARATION OF COPOLYMERS OF ALKYL METHACRYLATES AND MALEIC ANHYDRIDE EVONIK OPERATIONS GMBH (DE) 2020-04-29 EP disclosed
US-20170362360-A1 METHOD FOR THE PREPARATION OF COPOLYMERS OF ALKYL METHACRYLATES AND MALEIC ANHYDRIDE EVONIK OIL ADDITIVES GMBH (DE) 2017-12-21 US disclosed
EP-3233946-A1 METHOD FOR THE PREPARATION OF COPOLYMERS OF ALKYL METHACRYLATES AND MALEIC ANHYDRIDE Evonik Oil Additives GmbH (DE) 2017-10-25 EP disclosed
WO-2016097046-A1 METHOD FOR THE PREPARATION OF COPOLYMERS OF ALKYL METHACRYLATES AND MALEIC ANHYDRIDE EVONIK OIL ADDITIVES GMBH (DE) 2016-06-23 WO disclosed