⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL6624589 | 1.00 | — | — | |
| SCHEMBL4480097 | 0.77 | — | — | |
| Chloromethane SCHEMBL9860929 | 0.75 | — | — | |
| Carbon Monoxide SCHEMBL863533 | 0.75 | — | — | |
| Hypochlorous Acid SCHEMBL9161961 | 0.75 | — | — | |
| Carbon Monoxide SCHEMBL5984527 | 0.75 | — | — | |
| Fluoride SCHEMBL863576 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL221973 | 0.75 | — | — | |
| SCHEMBL8559679 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL597368 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210070771-A1 | COMMERCIALLY VIABLE SYNTHESIS OF CANTHARIDIN AND BIOACTIVE CANTHARIDIN DERIVATIVES | VERRICA PHARMACEUTICALS, INC. (US) | 2021-03-11 | — | — | US | disclosed |
| US-10745413-B2 | Commercially viable synthesis of cantharidin and bioactive cantharidin derivatives | VERRICA PHARMACEUTICALS, INC. (US) | 2020-08-18 | — | — | US | disclosed |
| US-20190002474-A1 | COMMERCIALLY VIABLE SYNTHESIS OF CANTHARIDIN AND BIOACTIVE CANTHARIDIN DERIVATIVES | VERRICA PHARMACEUTICALS INC. | 2019-01-03 | — | — | US | disclosed |
| EP-3233865-A2 | COMMERCIALLY VIABLE SYNTHESIS OF CANTHARIDIN AND BIOACTIVE CANTHARIDIN DERIVATIVES | Verrica Pharmaceuticals, Inc. (US) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016100732-A2 | COMMERCIALLY VIABLE SYNTHESIS OF CANTHARIDIN AND BIOACTIVE CANTHARIDIN DERIVATIVES | VERRICA PHARMACEUTICALS, INC. (US) | 2016-06-23 | — | — | WO | disclosed |