Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17839618 | 1.00 | NR1H4 (0.57) | NR1H4HSD17B13 | |
| SCHEMBL17839616 | 1.00 | NR1H4 (0.57) | NR1H4HSD17B13 | |
| SCHEMBL17856096 | 1.00 | NR1H4 (0.57) | NR1H4HSD17B13 | |
| SCHEMBL17848899 | 1.00 | NR1H4 (0.57) | NR1H4HSD17B13 | |
| SCHEMBL19189978 | 0.89 | NR1H4 (0.56) | NR1H4HSD17B13 | |
| SCHEMBL17839702 | 0.89 | NR1H4 (0.54) | NR1H4HSD17B13 | |
| SCHEMBL19189592 | 0.87 | NR1H4 (0.55) | NR1H4HSD17B13 | |
| SCHEMBL9957522 | 0.87 | NR1H4 (0.55) | NR1H4HSD17B13 | |
| SCHEMBL29555981 | 0.87 | NR1H4 (0.55) | NR1H4HSD17B13 | |
| SCHEMBL22654683 | 0.86 | NR1H4 (0.64) | NR1H4HSD17B13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233850-A1 | HYDROXY CONTAINING FXR (NR1H4) MODULATING COMPOUNDS | Gilead Sciences, Inc. (US) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016096115-A1 | HYDROXY CONTAINING FXR (NR1H4) MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2016-06-23 | — | — | WO | disclosed |