SCHEMBL17849122

SCHEMBL17849122

Cc1ccc(C(=O)Nc2nnnn2C)c(Cl)c1C

nearest known ligand 0.62

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.62
HPGD P15428 2/20 0.47
CYP1A2 P05177 2/20 0.47
CYP2C9 P11712 2/20 0.47
CYP2C19 P33261 2/20 0.47
ALDH1A1 P00352 1/20 0.43
LMNA P02545 2/20 0.37
GAA P10253 2/20 0.36
MMEL1 Q495T6 1/20 0.35
P2RX7 Q99572 1/20 0.35
WDR5 P61964 1/20 0.35
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HTT P42858 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18779295 0.88 POLB (0.59) POLBHPGDCYP1A2CYP2C9CYP2C19
SCHEMBL18496465 0.85 POLB (0.57) POLBHPGDCYP1A2CYP2C9CYP2C19
SCHEMBL28428304 0.84 POLB (0.56) POLBHPGDCYP1A2CYP2C9CYP2C19
SCHEMBL20413240 0.84 POLB (0.56) POLBHPGDCYP1A2CYP2C9CYP2C19
SCHEMBL21295295 0.82 POLB (0.66) POLBHPGDCYP1A2CYP2C9CYP2C19
SCHEMBL22245654 0.81 POLB (0.61) POLBHPGDCYP1A2CYP2C9CYP2C19
SCHEMBL17410531 0.80 POLB (0.53) POLBHPGDCYP1A2CYP2C9CYP2C19
SCHEMBL17397904 0.80 POLB (0.53) POLBHPGDCYP1A2CYP2C9CYP2C19
SCHEMBL16840517 0.79 POLB (0.56) POLBHPGDCYP1A2CYP2C9CYP2C19
SCHEMBL17946714 0.79 HPGD (0.72) POLBHPGDCYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9371315-B2 N-(tetrazol-5-yl)- and N-(triazol-5-yl)arylcarboxamide salts and use thereof as herbicides BAYER CROPSCIENCE AG (DE) 2016-06-21 US disclosed