Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 9/20 | 0.71 |
| ▸ | PIM1 | P11309 | 9/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.58 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18015043 | 1.00 | FYN (0.71) | FYNPIM1KCNH2MKNK1 | |
| SCHEMBL3040961 | 0.94 | FYN (0.80) | FYNPIM1KCNH2MKNK1 | |
| SCHEMBL3040966 | 0.94 | FYN (0.80) | FYNPIM1KCNH2MKNK1 | |
| SCHEMBL3042041 | 0.86 | FYN (0.80) | FYNPIM1KCNH2 | |
| SCHEMBL3042044 | 0.86 | FYN (0.80) | FYNPIM1KCNH2 | |
| SCHEMBL2943496 | 0.84 | FYN (0.80) | FYNPIM1KCNH2 | |
| SCHEMBL3041877 | 0.84 | FYN (0.80) | FYNPIM1KCNH2 | |
| SCHEMBL3041628 | 0.84 | PIM1 (0.66) | FYNPIM1KCNH2MKNK1 | |
| SCHEMBL3041625 | 0.84 | PIM1 (0.66) | FYNPIM1KCNH2MKNK1 | |
| SCHEMBL1055103 | 0.83 | FYN (1.00) | FYNPIM1MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9370515-B2 | Mixed lineage kinase inhibitors and method of treatments | Califia Bio, Inc. (US) | 2016-06-21 | — | — | US | disclosed |