Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 4/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16370885 | 0.85 | GAA (0.52) | GAARAPGEF4ALDH1A1KMT2AMAPT | |
| SCHEMBL10067072 | 0.80 | GAA (1.00) | GAARAPGEF4ALDH1A1KMT2AMAPT | |
| SCHEMBL170033 | 0.80 | GAA (1.00) | GAARAPGEF4ALDH1A1KMT2AMAPT | |
| SCHEMBL4400955 | 0.80 | GAA (1.00) | GAARAPGEF4ALDH1A1KMT2AMAPT | |
| SCHEMBL14445586 | 0.78 | GAA (0.54) | GAARAPGEF4ALDH1A1KMT2AMAPT | |
| SCHEMBL19318751 | 0.78 | GAA (0.54) | GAARAPGEF4ALDH1A1KMT2AMAPT | |
| Water SCHEMBL9619041 | 0.78 | GAA (0.94) | GAARAPGEF4ALDH1A1KMT2AMAPT | |
| SCHEMBL19318729 | 0.77 | GAA (0.52) | GAARAPGEF4ALDH1A1KMT2AMAPT | |
| SCHEMBL19318770 | 0.77 | GAA (0.52) | GAARAPGEF4ALDH1A1KMT2AMAPT | |
| Methylamine SCHEMBL11593292 | 0.75 | GAA (0.89) | GAARAPGEF4ALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9371297-B2 | Macrocyclic ghrelin receptor modulators and methods of using the same | OCERA THERAPEUTICS, INC. (US) | 2016-06-21 | — | — | US | disclosed |