Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10328997 | 1.00 | BACE1 (0.31) | BACE1BACE2 | |
| SCHEMBL10328658 | 0.85 | BACE1 (0.32) | BACE1BACE2 | |
| SCHEMBL15721339 | 0.85 | BACE1 (0.32) | BACE1BACE2 | |
| SCHEMBL15895194 | 0.85 | — | — | |
| SCHEMBL10328636 | 0.85 | — | — | |
| SCHEMBL10328683 | 0.84 | BACE1 (0.34) | BACE1BACE2 | |
| SCHEMBL15892961 | 0.84 | BACE1 (0.34) | BACE1BACE2 | |
| SCHEMBL10328681 | 0.82 | BACE1 (0.39) | BACE1BACE2 | |
| SCHEMBL15895228 | 0.82 | BACE1 (0.34) | BACE1BACE2 | |
| SCHEMBL10328668 | 0.82 | BACE1 (0.34) | BACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3034080-A1 | IMINOTHIADIAZINE DIOXIDE COMPOUNDS AS BACE INHIBITORS, COMPOSITIONS, AND THEIR USE | Merck Sharp & Dohme Corp. (US) | 2016-06-22 | — | — | EP | disclosed |