Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10329271 | 0.92 | BACE1 (0.59) | BACE1BACE2 | |
| SCHEMBL10329270 | 0.92 | BACE1 (0.68) | BACE1BACE2 | |
| SCHEMBL17850223 | 0.89 | BACE1 (0.59) | BACE1BACE2 | |
| SCHEMBL10329876 | 0.88 | BACE1 (0.59) | BACE1BACE2 | |
| SCHEMBL10328907 | 0.88 | BACE1 (0.60) | BACE1BACE2 | |
| SCHEMBL10329013 | 0.88 | BACE1 (0.57) | BACE1BACE2 | |
| SCHEMBL10329285 | 0.87 | BACE1 (0.63) | BACE1BACE2 | |
| SCHEMBL10329004 | 0.87 | BACE1 (0.60) | BACE1BACE2 | |
| SCHEMBL15892980 | 0.86 | BACE1 (0.59) | BACE1BACE2 | |
| SCHEMBL10329269 | 0.86 | BACE1 (0.55) | BACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3034080-A1 | IMINOTHIADIAZINE DIOXIDE COMPOUNDS AS BACE INHIBITORS, COMPOSITIONS, AND THEIR USE | Merck Sharp & Dohme Corp. (US) | 2016-06-22 | — | — | EP | disclosed |