Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 7/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | F11 | P03951 | 2/20 | 0.45 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.45 |
| ▸ | PDE5A | O76074 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | HMGCR | P04035 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26822757 | 1.00 | PTPN1 (0.49) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL15833434 | 0.99 | PTPN1 (0.48) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL16299427 | 0.99 | PTPN1 (0.48) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL13447793 | 0.96 | TSHR (0.48) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL17850327 | 0.96 | TSHR (0.48) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL14413572 | 0.96 | PTPN1 (0.51) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL23763279 | 0.95 | PTPN1 (0.45) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL17850337 | 0.95 | TSHR (0.47) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL9179303 | 0.92 | PTPN1 (0.52) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL10273417 | 0.91 | PTPN1 (0.44) | PTPN1USP2MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3034510-A1 | OLIGONUCLEOTIDES COMPRISING A C5-MODIFIED PYRIMIDINE | Alnylam Pharmaceuticals Inc. (US) | 2016-06-22 | — | — | EP | disclosed |