Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | HMGCR | P04035 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17850321 | 1.00 | TSHR (0.55) | TSHRPTPN1USP2KMT2AMEN1 | |
| SCHEMBL13447782 | 1.00 | TSHR (0.55) | TSHRPTPN1USP2KMT2AMEN1 | |
| SCHEMBL22022529 | 0.99 | TSHR (0.53) | TSHRPTPN1USP2KMT2AMEN1 | |
| SCHEMBL17850298 | 0.95 | PTPN1 (0.56) | TSHRPTPN1USP2KMT2AMEN1 | |
| SCHEMBL22455860 | 0.95 | PTPN1 (0.56) | TSHRPTPN1USP2KMT2AMEN1 | |
| SCHEMBL13271795 | 0.95 | PTPN1 (0.56) | TSHRPTPN1USP2KMT2AMEN1 | |
| SCHEMBL20730007 | 0.95 | PTPN1 (0.56) | TSHRPTPN1USP2KMT2AMEN1 | |
| SCHEMBL13250762 | 0.95 | PTPN1 (0.56) | TSHRPTPN1USP2KMT2AMEN1 | |
| SCHEMBL14405192 | 0.95 | PTPN1 (0.56) | TSHRPTPN1USP2KMT2AMEN1 | |
| SCHEMBL18068236 | 0.95 | PTPN1 (0.56) | TSHRPTPN1USP2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3034510-A1 | OLIGONUCLEOTIDES COMPRISING A C5-MODIFIED PYRIMIDINE | Alnylam Pharmaceuticals Inc. (US) | 2016-06-22 | — | — | EP | disclosed |