Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 9/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10194971 | 0.83 | FLT3 (0.55) | FLT3KDM4ENPC1RAB9AKMT2A | |
| SCHEMBL15317779 | 0.73 | FLT3 (0.51) | FLT3KDM4ENPC1RAB9AKMT2A | |
| SCHEMBL10194719 | 0.71 | FLT3 (0.51) | FLT3KDM4ENPC1RAB9AKMT2A | |
| SCHEMBL12074236 | 0.71 | — | — | |
| SCHEMBL14859968 | 0.71 | — | — | |
| SCHEMBL9952109 | 0.71 | FLT3 (0.49) | FLT3KDM4ENPC1RAB9AKMT2A | |
| SCHEMBL31172183 | 0.69 | FLT3 (1.00) | FLT3 | |
| SCHEMBL31172344 | 0.69 | FLT3 (1.00) | FLT3 | |
| SCHEMBL31172392 | 0.69 | FLT3 (1.00) | FLT3 | |
| SCHEMBL10194717 | 0.69 | KDM4E (0.49) | FLT3KDM4ENPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655357-B1 | INDAZOLYL TRIAZOLE DERIVATIVES AS IRAK INHIBITORS | MERCK SERONO SA (CH) | 2016-06-22 | — | — | EP | disclosed |