Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 19/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17835774 | 1.00 | NOX1 (0.67) | NOX1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL17835878 | 0.87 | NOX1 (0.79) | NOX1 | |
| SCHEMBL17835548 | 0.87 | NOX1 (0.79) | NOX1 | |
| SCHEMBL17835653 | 0.87 | NOX1 (0.79) | NOX1 | |
| SCHEMBL31317816 | 0.84 | NOX1 (0.82) | NOX1 | |
| SCHEMBL17835484 | 0.84 | NOX1 (0.82) | NOX1 | |
| SCHEMBL17835483 | 0.84 | NOX1 (0.82) | NOX1 | |
| SCHEMBL17835763 | 0.84 | NOX1 (0.82) | NOX1 | |
| SCHEMBL17835486 | 0.83 | NPC1 (0.68) | NOX1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL17835687 | 0.82 | NOX1 (0.74) | NOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3034500-A1 | Amido thiazole derivatives as NADPH oxidase inhibitors | GENKYOTEX SA (CH) | 2016-06-22 | — | — | EP | disclosed |