Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHIA | Q9BZP6 | 17/20 | 0.42 |
| ▸ | CHIT1 | Q13231 | 16/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17853355 | 0.79 | CHIA (0.42) | CHIACHIT1 | |
| SCHEMBL16826006 | 0.77 | CHIA (0.70) | CHIACHIT1KCNH2 | |
| SCHEMBL16826256 | 0.77 | CHIA (0.71) | CHIACHIT1KCNH2 | |
| Hydrochloric Acid SCHEMBL21638347 | 0.76 | CHIA (0.69) | CHIACHIT1KCNH2 | |
| SCHEMBL16825846 | 0.76 | CHIA (0.69) | CHIACHIT1KCNH2 | |
| SCHEMBL16826076 | 0.75 | CHIA (0.70) | CHIACHIT1KCNH2 | |
| SCHEMBL16825876 | 0.74 | CHIA (0.70) | CHIACHIT1KCNH2 | |
| SCHEMBL18129147 | 0.74 | CHIA (0.57) | CHIACHIT1KCNH2 | |
| SCHEMBL18129092 | 0.74 | CHIA (0.57) | CHIACHIT1KCNH2 | |
| SCHEMBL16825994 | 0.73 | CHIA (0.50) | CHIACHIT1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016099311-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS ACIDIC MAMMALIAN CHITINASE INHIBITORS | OncoArendi Therapeutics Sp. z o.o. (PL) | 2016-06-23 | — | — | WO | disclosed |
| US-20150166533-A1 | NOVEL 1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE DERIVATIVES SUBSTITUTED WITH BENZIMIDAZOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | JANSSEN R&D IRELAND (US) | 2015-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150166533-A1 | NOVEL 1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE DERIVATIVES SUBSTITUTED WITH BENZIMIDAZOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | ZC3HAV1, ZC3HAV1L, SARS1 | CHIA 4039/4885CHIT1 3457/4885KCNH2 3120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.