Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | DAO | P14920 | 1/20 | 0.61 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.61 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.52 |
| ▸ | CES2 | O00748 | 2/20 | 0.52 |
| ▸ | CES1 | P23141 | 2/20 | 0.52 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.51 |
| ▸ | KMO | O15229 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL10907428 | 1.00 | TSHR (0.61) | TSHRDAONAPRTSRD5A2CES2 | |
| Benzoic Acid SCHEMBL28488472 | 0.96 | TSHR (0.61) | TSHRDAONAPRTSRD5A2CES2 | |
| Benzoic Acid SCHEMBL28441353 | 0.85 | TSHR (0.58) | TSHRDAONAPRTSRD5A2CES2 | |
| Biphenyl SCHEMBL10897390 | 0.83 | TSHR (0.61) | TSHRDAONAPRTSRD5A2CES2 | |
| Biphenyl SCHEMBL26606260 | 0.83 | TSHR (0.61) | TSHRDAONAPRTSRD5A2CES2 | |
| Benzoic Acid SCHEMBL27642012 | 0.82 | TSHR (0.67) | TSHRDAONAPRTSRD5A2CES2 | |
| Benzoic Acid SCHEMBL1786143 | 0.82 | TSHR (0.67) | TSHRDAONAPRTSRD5A2CES2 | |
| Benzoic Acid SCHEMBL4089578 | 0.81 | TSHR (0.82) | TSHRDAONAPRTSRD5A2CES2 | |
| Benzoic Acid SCHEMBL9456932 | 0.81 | TSHR (0.82) | TSHRDAONAPRTSRD5A2CES2 | |
| Benzoic Acid SCHEMBL4094227 | 0.81 | TSHR (0.82) | TSHRDAONAPRTSRD5A2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050239636-A1 | Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2005-10-27 | — | — | US | claimed |
| CN-113105690-B | Heterophasic propylene polymer material and use thereof | 住友化学株式会社 | 2024-03-01 | — | — | CN | disclosed |
| CN-111836855-B | Heterophasic propylene polymer material | 住友化学株式会社 | 2023-09-22 | — | — | CN | disclosed |
| CN-115926028-A | Process for producing solid catalyst component for olefin polymerization, process for producing catalyst for olefin polymerization, and process for producing olefin polymer | 住友化学株式会社 | 2023-04-07 | — | — | CN | disclosed |
| CN-110382574-B | Heterophasic propylene polymer material and propylene resin composition | 住友化学株式会社 | 2023-03-31 | — | — | CN | disclosed |
| CN-114057913-A | Solid catalyst component for olefin polymerization | 住友化学株式会社 | 2022-02-18 | — | — | CN | disclosed |
| CN-113461842-A | Solid catalyst component for olefin polymerization | 住友化学株式会社 | 2021-10-01 | — | — | CN | disclosed |
| CN-113105690-A | Heterophasic propylene polymer material and use thereof | 住友化学株式会社 | 2021-07-13 | — | — | CN | disclosed |
| CN-109563324-B | Heterophasic propylene polymeric material | 住友化学株式会社 | 2021-06-18 | — | — | CN | disclosed |
| CN-111836855-A | Heterophasic propylene polymeric material | 住友化学株式会社 | 2020-10-27 | — | — | CN | disclosed |
| US-7388061-B2 | Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2008-06-17 | — | — | US | disclosed |
| US-7332455-B2 | Catalyst component and catalyst for olefin polymerization as well as use thereof | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2008-02-19 | — | — | US | disclosed |
| CN-1310963-C | Catalyst component for olefin polymerization reaction and catalyst | CHINA PETROCHEMICAL CORP (CN) | 2007-04-18 | — | — | CN | disclosed |
| EP-1666505-A1 | CATALYST COMPONENTS CATALYSTS FOR OLEFINIC POLYMERIZATION AND THE USE THEREOF | China Petroleum & Chemical Corporation (CN) | 2006-06-07 | — | — | EP | disclosed |
| CN-1743346-A | Catalyst component for olefinic polymerization and its catalyst | CHINA PETROCHEMICAL CORP (CN) | 2006-03-08 | — | — | CN | disclosed |
| CN-1743348-A | Catalyst component for olefinic polymerization and its catalyst | CHINA PETROCHEMICAL CORP (CN) | 2006-03-08 | — | — | CN | disclosed |
| US-20050239636-A1 | Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2005-10-27 | — | — | US | disclosed |
| US-20050119427-A1 | Catalyst component and catalyst for olefin polymerization as well as use thereof | BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2005-06-02 | — | — | US | disclosed |
| CN-1552741-A | Catalyst component for olefin polymerization reaction and catalyst | 中国石油化工股份有限公司 | 2004-12-08 | — | — | CN | disclosed |
| CN-1446197-A | Oxygenated esters of 4-iodo phenylamino benzhydroxamic acids | WARNER LAMBERT CO (US) | 2003-10-01 | — | — | CN | disclosed |