SCHEMBL1785452

SCHEMBL1785452

C=[C]CCCCCCCCCCCCCCCC

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
THRB P10828 1/20 0.50
PTPN7 P35236 3/20 0.39
HMGCR P04035 1/20 0.39
DNM1 Q05193 5/20 0.38
ALDH1A1 P00352 2/20 0.38
LMNA P02545 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
HSD17B10 Q99714 1/20 0.38
SLC22A1 O15245 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16673360 1.00 TSHR (0.50) TSHRTHRBPTPN7HMGCRDNM1
SCHEMBL9785166 1.00 TSHR (0.50) TSHRTHRBPTPN7HMGCRDNM1
SCHEMBL9785134 1.00 TSHR (0.50) TSHRTHRBPTPN7HMGCRDNM1
SCHEMBL999183 1.00 TSHR (0.50) TSHRTHRBPTPN7HMGCRDNM1
SCHEMBL16673485 1.00 TSHR (0.50) TSHRTHRBPTPN7HMGCRDNM1
SCHEMBL9436082 1.00 TSHR (0.50) TSHRTHRBPTPN7HMGCRDNM1
SCHEMBL811812 1.00 TSHR (0.50) TSHRTHRBPTPN7HMGCRDNM1
SCHEMBL2166417 1.00 TSHR (0.50) TSHRTHRBPTPN7HMGCRDNM1
SCHEMBL16673619 1.00 TSHR (0.50) TSHRTHRBPTPN7HMGCRDNM1
SCHEMBL419739 1.00 TSHR (0.50) TSHRTHRBPTPN7HMGCRDNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109422850-A The fluorine-containing macromole emulsifying agent of self-crosslinking, the fluorine-containing latex containing the emulsifier, its method of preparation and use 浙江大学 2019-03-05 CN claimed
CN-105985496-B A kind of anionic functional fluoropolymer and preparation method thereof 浙江大学 2018-05-15 CN claimed
CN-105985495-B A kind of cationic functional fluoropolymer and preparation method thereof 浙江大学 2018-05-15 CN claimed
CN-105985494-B A kind of nonionic functionalization fluoropolymer and preparation method thereof 浙江大学 2018-05-15 CN claimed
US-4992080-A Crude oil mixture having a depressed pour point CONOCO INC. (US) 1991-02-12 US claimed
EP-3083243-B1 PRE-EXFOLIATED LAYERED MATERIALS BYK USA INC (US) 2020-05-13 EP disclosed
CN-110520473-A Injection molded resin combination SEKISUI CHEMICAL CO LTD 2019-11-29 CN disclosed
US-10414900-B2 Pre-exfoliated layered material BYK USA INC. (US) 2019-09-17 US disclosed
CN-109422850-A The fluorine-containing macromole emulsifying agent of self-crosslinking, the fluorine-containing latex containing the emulsifier, its method of preparation and use 浙江大学 2019-03-05 CN disclosed
CN-109312254-A Aqueous compositions for hard surface applications with enhanced stability 凯密特尔美国公司 2019-02-05 CN disclosed
CN-105985495-B A kind of cationic functional fluoropolymer and preparation method thereof 浙江大学 2018-05-15 CN disclosed
CN-105985496-B A kind of anionic functional fluoropolymer and preparation method thereof 浙江大学 2018-05-15 CN disclosed
US-20140030744-A1 Means and Methods for Diagnosing Gastric Bypass and Conditions Related Thereto INSERM INSTITUTE NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) 2014-01-30 US disclosed
CN-102355833-A A packaging and applicator device for at least one solid cosmetic composition OREAL 2012-02-15 CN disclosed
US-20110113863-A1 MEANS AND METHODS DIAGNOSING GASTRIC BYPASS AND CONDITIONS RELATED THERETO METANOMICS HEALTH GMBH (DE) 2011-05-19 US disclosed
WO-2006038735-A1 RESIN COMPOSITION FOR OPTICAL PACKAGING MATERIAL AND PROCESS FOR PREPARING THE SAME, AND OPTICAL PACKAGING MATERIAL, OPTICAL PACKAGING COMPONENT, AND OPTICAL MODULE NIPPON SHOKUBAI CO., LTD. (JP) 2006-04-13 WO disclosed
EP-0137271-B1 METHOD OF IMPROVING THE LIGHT RESISTANCE OF A DYE IMAGE KONICA CORPORATION (JP) 1987-11-04 EP disclosed
US-4540653-A METAL COMPLEX, ANILINO COUPLER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1985-09-10 US disclosed
EP-0137271-A2 Method of improving the light resistance of a dye image KONICA CORPORATION (JP) 1985-04-17 EP disclosed
US-4501928-A LEAP DOIL, VINYL CHLORIDE POLYMER, NON-REACTION- CURABLE ADHESIVE DAINICHI-NIPPON CABLES, LTD. (JP) 1985-02-26 US disclosed