⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL890877 | 0.80 | — | — | |
| SCHEMBL27763216 | 0.77 | TP53 (0.38) | — | |
| SCHEMBL28434132 | 0.77 | TP53 (0.38) | — | |
| SCHEMBL28074189 | 0.77 | TP53 (0.38) | — | |
| SCHEMBL14754136 | 0.74 | — | — | |
| SCHEMBL890928 | 0.70 | — | — | |
| SCHEMBL3480692 | 0.69 | — | — | |
| SCHEMBL4686073 | 0.68 | — | — | |
| SCHEMBL14224003 | 0.68 | — | — | |
| SCHEMBL28102454 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8796229-B2 | Feedback prodrug | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2014-08-05 | — | — | US | disclosed |
| US-8172873-B2 | Shape memory polymers | UNIVERSITY OF ROCHESTER (US) | 2012-05-08 | — | — | US | disclosed |
| US-20120058960-A1 | FEEDBACK PRODRUG | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| US-20110251364-A1 | Shape Memory Polymers | NATIONAL SCIENCE FOUNDATION | 2011-10-13 | — | — | US | disclosed |
| US-7935131-B2 | Shape memory polymers | UNIVERSITY OF ROCHESTER (US) | 2011-05-03 | — | — | US | disclosed |
| US-20100160207-A1 | Feedback Prodrug | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2010-06-24 | — | — | US | disclosed |
| US-20080177303-A1 | Shape memory polymers | ROCHESTER, UNIVERSITY OF | 2008-07-24 | — | — | US | disclosed |