Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17837850 | 0.90 | AXL (0.61) | AXLMAP4K4 | |
| SCHEMBL17857692 | 0.89 | AXL (0.58) | AXLMAP4K4 | |
| SCHEMBL17837592 | 0.88 | AXL (0.75) | AXL | |
| SCHEMBL17861734 | 0.77 | AXL (0.61) | AXLMAP4K4 | |
| SCHEMBL17837684 | 0.76 | AXL (0.63) | AXLMAP4K4 | |
| SCHEMBL17837946 | 0.76 | AXL (0.75) | AXL | |
| SCHEMBL17837549 | 0.74 | AXL (1.00) | AXL | |
| SCHEMBL21240819 | 0.74 | AXL (1.00) | AXL | |
| SCHEMBL17837841 | 0.74 | AXL (0.52) | AXLMAP4K4 | |
| SCHEMBL18625407 | 0.73 | AXL (1.00) | AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016097918-A1 | PYRIMIDINE AND TRIAZINE DERIVATIVES AND THEIR USE AS AXL INHIBITORS | PFIZER INC. (US) | 2016-06-23 | — | — | WO | disclosed |