Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21254771 | 0.80 | AXL (0.77) | AXL | |
| SCHEMBL17857768 | 0.80 | AXL (0.80) | AXL | |
| SCHEMBL18625747 | 0.79 | AXL (0.84) | AXL | |
| SCHEMBL17837856 | 0.79 | AXL (1.00) | AXL | |
| SCHEMBL17837576 | 0.78 | AXL (1.00) | AXL | |
| SCHEMBL17857770 | 0.77 | AXL (0.77) | AXL | |
| SCHEMBL17837409 | 0.76 | AXL (0.83) | AXL | |
| SCHEMBL18625296 | 0.75 | AXL (0.61) | AXL | |
| SCHEMBL17861741 | 0.75 | AXL (1.00) | AXL | |
| SCHEMBL17837376 | 0.74 | AXL (1.00) | AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016097918-A1 | PYRIMIDINE AND TRIAZINE DERIVATIVES AND THEIR USE AS AXL INHIBITORS | PFIZER INC. (US) | 2016-06-23 | — | — | WO | disclosed |