SCHEMBL17860343 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	PLCG1	P19174	4/20	0.54

▸	PLCB3	Q01970	4/20	0.54

▸	CASP6	P55212	1/20	0.52

▸	PAX8	Q06710	10/20	0.49

▸	MTTP	P55157	2/20	0.39

▸	MEN1	O00255	2/20	0.38

▸	KMT2A	Q03164	2/20	0.38

▸	RXFP1	Q9HBX9	1/20	0.38

▸	MAPT	P10636	2/20	0.36

▸	ALDH1A1	P00352	1/20	0.36

▸	TP53	P04637	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL17860354	0.90	PLCG1 (0.57)	PLCG1PLCB3CASP6PAX8MEN1
SCHEMBL17860414	0.90	PLCG1 (0.57)	PLCG1PLCB3CASP6PAX8MEN1
SCHEMBL17860379	0.89	PLCG1 (0.60)	PLCG1PLCB3CASP6PAX8MEN1
SCHEMBL17860447	0.86	PLCG1 (0.56)	PLCG1PLCB3CASP6PAX8MEN1
SCHEMBL17860472	0.86	PLCG1 (0.59)	PLCG1PLCB3CASP6PAX8MEN1
SCHEMBL17860298	0.86	PLCG1 (0.62)	PLCG1PLCB3CASP6PAX8MEN1
SCHEMBL17860479	0.86	PLCG1 (0.57)	PLCG1PLCB3CASP6PAX8MEN1
SCHEMBL17860474	0.86	PLCG1 (0.57)	PLCG1PLCB3CASP6PAX8MEN1
SCHEMBL17860382	0.85	PLCG1 (0.59)	PLCG1PLCB3CASP6PAX8MEN1
SCHEMBL17860445	0.85	PLCG1 (0.60)	PLCG1PLCB3CASP6PAX8MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2016100711-A1	MODULATORS OF HEPATIC LIPOPROTEIN METABOLISM	THE BROAD INSTITUTE, INC. (US)	2016-06-23	—	—	WO	disclosed