Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL824523 | 0.86 | CYP4F2 (0.41) | CYP4F2CYP4A11HMGCRCHRM2CHRM4 | |
| SCHEMBL2179864 | 0.84 | CYP4F2 (0.39) | CYP4F2CYP4A11HMGCR | |
| SCHEMBL13667082 | 0.82 | CYP4F2 (0.42) | CYP4F2CYP4A11TSHRACHE | |
| SCHEMBL1105061 | 0.82 | HCAR2 (0.39) | CYP4F2CYP4A11HMGCRCHRM1TSHR | |
| SCHEMBL9883777 | 0.80 | CYP4F2 (0.41) | CYP4F2CYP4A11HMGCRCHRM2CHRM4 | |
| SCHEMBL13667073 | 0.80 | CYP4F2 (0.46) | CYP4F2CYP4A11TSHRACHE | |
| SCHEMBL75751 | 0.80 | CYP4F2 (0.46) | CYP4F2CYP4A11HMGCRCHRM2CHRM4 | |
| SCHEMBL10686206 | 0.79 | POLB (0.43) | CYP4F2CYP4A11 | |
| SCHEMBL837877 | 0.78 | TSHR (0.38) | CYP4F2CYP4A11HMGCRCHRM2CHRM4 | |
| SCHEMBL2680639 | 0.78 | CYP4F2 (0.40) | CYP4F2CYP4A11HMGCRCHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070110-A1 | POLYMERS HAVING ORTHOGONAL REACTIVE GROUPS AND USES THEREOF | NVS Technologies Inc. (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2016100578-A2 | ANTIMICROBIAL POLYMYXINS FOR TREATMENT OF BACTERIAL INFECTIONS | MICURX PHARMACEUTICALS, INC. (US) | 2016-06-23 | — | — | WO | disclosed |