Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 7/20 | 0.57 |
| ▸ | P2RY2 | P41231 | 16/20 | 0.56 |
| ▸ | P2RY4 | P51582 | 10/20 | 0.56 |
| ▸ | POLA1 | P09884 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17863920 | 1.00 | P2RY6 (0.57) | P2RY6P2RY2P2RY4POLA1 | |
| SCHEMBL16368057 | 0.92 | P2RY6 (0.58) | P2RY6P2RY2P2RY4POLA1 | |
| SCHEMBL17860932 | 0.92 | P2RY6 (0.58) | P2RY6P2RY2P2RY4POLA1 | |
| SCHEMBL17861898 | 0.91 | P2RY6 (0.57) | P2RY6P2RY2P2RY4POLA1 | |
| SCHEMBL15070635 | 0.91 | P2RY6 (0.57) | P2RY6P2RY2P2RY4POLA1 | |
| SCHEMBL17860775 | 0.91 | P2RY6 (0.57) | P2RY6P2RY2P2RY4POLA1 | |
| SCHEMBL17863963 | 0.91 | P2RY6 (0.57) | P2RY6P2RY2P2RY4POLA1 | |
| SCHEMBL15070588 | 0.91 | P2RY6 (0.57) | P2RY6P2RY2P2RY4POLA1 | |
| SCHEMBL16374024 | 0.91 | P2RY2 (0.58) | P2RY6P2RY2P2RY4POLA1 | |
| SCHEMBL16374047 | 0.89 | P2RY6 (0.56) | P2RY6P2RY2P2RY4POLA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100569-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | ALIOS BIOPHARMA, INC. (US) | 2016-06-23 | — | — | WO | disclosed |