Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 3/20 | 0.34 |
| ▸ | NOS1 | P29475 | 3/20 | 0.34 |
| ▸ | NOS2 | P35228 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16486923 | 0.89 | SMN1; SMN2 (0.50) | SMN1; SMN2CA1CA2POLBCA14 | |
| SCHEMBL12875894 | 0.84 | SMN1; SMN2 (0.46) | SMN1; SMN2CA1CA2POLBCA14 | |
| SCHEMBL5520671 | 0.84 | SMN1; SMN2 (0.46) | SMN1; SMN2CA1CA2POLBCA14 | |
| SCHEMBL12875891 | 0.84 | SMN1; SMN2 (0.46) | SMN1; SMN2CA1CA2POLBCA14 | |
| SCHEMBL17000158 | 0.84 | SMN1; SMN2 (0.46) | SMN1; SMN2CA1CA2POLBCA14 | |
| SCHEMBL15041053 | 0.84 | CA1 (0.43) | SMN1; SMN2CA1CA2POLBCA14 | |
| SCHEMBL11041537 | 0.84 | CA1 (0.43) | SMN1; SMN2CA1CA2POLBCA14 | |
| SCHEMBL12890253 | 0.84 | CA1 (0.43) | SMN1; SMN2CA1CA2POLBCA14 | |
| SCHEMBL8223673 | 0.84 | CA1 (0.43) | SMN1; SMN2CA1CA2POLBCA14 | |
| SCHEMBL15041052 | 0.84 | CA1 (0.43) | SMN1; SMN2CA1CA2POLBCA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160175492-A1 | MEDICAL DEVICE AND METHOD FOR PRODUCING SAME | TERUMO KABUSHIKI KAISHA (JP) | 2016-06-23 | — | — | US | disclosed |