SCHEMBL1786261

SCHEMBL1786261

CC(C)(OC(=O)c1ccccc1)C(C)(C)OC(=O)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.59
TDP1 Q9NUW8 5/20 0.59
ALDH1A1 P00352 3/20 0.59
HSD17B10 Q99714 1/20 0.59
LMNA P02545 2/20 0.56
F2 P00734 1/20 0.56
CYP2D6 P10635 2/20 0.54
CYP1A2 P05177 1/20 0.54
CYP2C19 P33261 1/20 0.54
TP53 P04637 1/20 0.52
MAPT P10636 2/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
MAPK1 P28482 1/20 0.50
HIF1A Q16665 1/20 0.50
PDCD1 Q15116 1/20 0.46
CD274 Q9NZQ7 1/20 0.46
KMT2A Q03164 2/20 0.45
SLC6A3 Q01959 2/20 0.45
POLB P06746 1/20 0.45
SLC6A2 P23975 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetophenone SCHEMBL11149993 0.92 TSHR (0.52) TSHRTDP1ALDH1A1HSD17B10LMNA
SCHEMBL5158787 0.90 TDP1 (0.53) TSHRTDP1ALDH1A1HSD17B10LMNA
SCHEMBL18131450 0.88 TSHR (0.52) TSHRTDP1ALDH1A1HSD17B10LMNA
SCHEMBL27622624 0.88 TDP1 (0.52) TSHRTDP1ALDH1A1HSD17B10LMNA
SCHEMBL29199324 0.86 TDP1 (0.64) TSHRTDP1ALDH1A1HSD17B10LMNA
Hydrogen Peroxide SCHEMBL28474133 0.86 TDP1 (0.64) TSHRTDP1ALDH1A1HSD17B10LMNA
Hydrogen Peroxide SCHEMBL28425777 0.86 TDP1 (0.64) TSHRTDP1ALDH1A1HSD17B10LMNA
SCHEMBL260960 0.86 TDP1 (0.64) TSHRTDP1ALDH1A1HSD17B10LMNA
SCHEMBL1953844 0.86 TSHR (0.59) TSHRTDP1ALDH1A1HSD17B10LMNA
SCHEMBL1785487 0.86 CYP2D6 (0.51) TSHRTDP1ALDH1A1HSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3486263-A2 SELF-LIMITING CATALYST COMPOSITION WITH NO SILANE W.R. Grace & CO. - CONN. (US) 2019-05-22 EP disclosed
EP-2185600-B1 SELF-LIMITING CATALYST COMPOSITION WITH NO SILANE GRACE W R & CO (US) 2018-10-31 EP disclosed
US-9796796-B2 Self-limiting catalyst composition with No silane W. R. GRACE & CO.-CONN. (US) 2017-10-24 US disclosed
EP-1666505-B1 CATALYST COMPONENTS CATALYSTS FOR OLEFINIC POLYMERIZATION AND THE USE THEREOF CHINA PETROLEUM & CHEMICAL (CN) 2016-03-23 EP disclosed
US-20130109789-A1 OLEFIN POLYMERIZATION CATALYST, PROCESS FOR PRODUCING OLEFIN POLYMER, POLYPROPYLENE RESIN COMPOSITION AND ARTICLE COMPRISING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-02 US disclosed
US-20110124491-A1 Self-Limiting Catalyst Composition with No Silane W. R. GRACE & CO.-CONN. 2011-05-26 US disclosed
US-7862868-B2 Ink-jet recording material FERRANIA TECHNOLOGIES, S.P.A. (IT) 2011-01-04 US disclosed
EP-2185600-A1 SELF-LIMITING CATALYST COMPOSITION WITH NO SILANE Dow Global Technologies Inc. (US) 2010-05-19 EP disclosed
WO-2009029447-A1 SELF-LIMITING CATALYST COMPOSITION WITH NO SILANE DOW GLOBAL TECHNOLOGIES INC. (US) 2009-03-05 WO disclosed
US-20080138544-A1 Ink-Jet Recording Material FERRANIA TECHNOLOGIES, S.P.A. 2008-06-12 US disclosed
US-7332455-B2 Catalyst component and catalyst for olefin polymerization as well as use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-02-19 US disclosed
WO-2006077052-A1 INK-JET RECORDING MATERIAL FERRANIA TECHNOLOGIES S.P.A. (IT) 2006-07-27 WO disclosed
EP-1666505-A1 CATALYST COMPONENTS CATALYSTS FOR OLEFINIC POLYMERIZATION AND THE USE THEREOF China Petroleum & Chemical Corporation (CN) 2006-06-07 EP disclosed
WO-2006002780-A2 INK-JET RECORDING MATERIAL FERRANIA TECHNOLOGIES S.P.A (IT) 2006-01-12 WO disclosed
US-20050119427-A1 Catalyst component and catalyst for olefin polymerization as well as use thereof BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-06-02 US disclosed