Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 20/20 | 0.63 |
| ▸ | OXTR | P30559 | 2/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.44 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16178114 | 1.00 | AVPR1B (0.63) | AVPR1BOXTRAVPR1AAVPR2 | |
| SCHEMBL1590460 | 0.90 | AVPR1B (0.55) | AVPR1BOXTRAVPR1AAVPR2 | |
| SCHEMBL1588385 | 0.89 | AVPR1B (0.50) | AVPR1BOXTRAVPR1AAVPR2 | |
| SCHEMBL1589023 | 0.85 | AVPR1B (0.46) | AVPR1BOXTRAVPR1AAVPR2 | |
| SCHEMBL3841463 | 0.84 | AVPR1B (0.66) | AVPR1BOXTRAVPR1AAVPR2 | |
| SCHEMBL1786609 | 0.83 | AVPR1B (0.73) | AVPR1B | |
| SCHEMBL1465435 | 0.80 | AVPR1B (0.55) | AVPR1BOXTRAVPR1AAVPR2 | |
| SCHEMBL1465439 | 0.80 | AVPR1B (0.55) | AVPR1BOXTRAVPR1AAVPR2 | |
| SCHEMBL1465433 | 0.80 | AVPR1B (0.55) | AVPR1BOXTRAVPR1AAVPR2 | |
| SCHEMBL6521339 | 0.79 | AVPR1B (0.64) | AVPR1BOXTRAVPR1AAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9657002-B2 | Oxindole derivatives carrying an oxetane substituent and use thereof for treating vassopressin-related diseases | AbbVie Deutschland GmbH & Co. KG (DE) | 2017-05-23 | — | — | US | disclosed |
| US-20150352110-A1 | SUBSTITUTED OXINDOLE DERIVATIVES AND THEIR USE AS VASOPRESSIN RECEPTOR LIGANDS | ABBVIE DEUTSCHLAND (DE) | 2015-12-10 | — | — | US | disclosed |
| US-20140315918-A1 | Oxindole Derivatives Carrying An Oxetane Substituent and Use Thereof For Treating Vassopressin-Related Diseases | AbbVie Deutschland GmbH & Co. KG (DE) | 2014-10-23 | — | — | US | disclosed |
| US-20110124658-A1 | SUBSTITUTED OXINDOLE DERIVATIVES AND THEIR USE AS VASOPRESSIN RECEPTOR LIGANDS | ABBOTT GMBH & CO. KG (DE) | 2011-05-26 | — | — | US | disclosed |
| WO-2009071691-A2 | OXINDOLE DERIVATIVES AND THE USE THEREOF AS A MEDICATION | ABBOTT GMBH & CO. KG (DE) | 2009-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150352110-A1 | SUBSTITUTED OXINDOLE DERIVATIVES AND THEIR USE AS VASOPRESSIN RECEPTOR LIGANDS | AVPR2, AVPR1B, AVPR1A | AVPR1B 2/4885OXTR 4/4885AVPR1A 3/4885 |
| US-20110124658-A1 | SUBSTITUTED OXINDOLE DERIVATIVES AND THEIR USE AS VASOPRESSIN RECEPTOR LIGANDS | AVPR2, AVPR1B, AVPR1A | AVPR1B 2/4885OXTR 4/4885AVPR1A 3/4885 |
| US-20140315918-A1 | Oxindole Derivatives Carrying An Oxetane Substituent and Use Thereof For Treating Vassopressin-Related Diseases | AVPR2, AVPR1B, AVPR1A | AVPR1B 2/4885OXTR 7/4885AVPR1A 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.