Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.54 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.51 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2288108 | 0.87 | SLC29A1 (0.76) | SLC29A1ADORA3TP53TDP1NPC1 | |
| SCHEMBL21011278 | 0.87 | SLC29A1 (0.76) | SLC29A1ADORA3TP53TDP1NPC1 | |
| SCHEMBL27183207 | 0.87 | SLC29A1 (0.76) | SLC29A1ADORA3TP53TDP1NPC1 | |
| SCHEMBL23982158 | 0.87 | SLC29A1 (0.76) | SLC29A1ADORA3TP53TDP1NPC1 | |
| SCHEMBL2288114 | 0.87 | SLC29A1 (0.76) | SLC29A1ADORA3TP53TDP1NPC1 | |
| SCHEMBL23982135 | 0.87 | SLC29A1 (0.76) | SLC29A1ADORA3TP53TDP1NPC1 | |
| SCHEMBL14873532 | 0.87 | SLC29A1 (0.76) | SLC29A1ADORA3TP53TDP1NPC1 | |
| SCHEMBL17875220 | 0.86 | SLC29A1 (0.60) | SLC29A1ADORA3TP53TDP1NPC1 | |
| SCHEMBL1796246 | 0.86 | SLC29A1 (0.60) | SLC29A1ADORA3TP53TDP1NPC1 | |
| SCHEMBL10186161 | 0.86 | SLC29A1 (0.60) | SLC29A1ADORA3TP53TDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402334-B1 | Inhibitors of E1 Activating Enzymes | MILLENNIUM PHARM INC (US) | 2016-06-29 | — | — | EP | claimed |