Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 3/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22286471 | 1.00 | HDAC4 (0.58) | HDAC4HDAC1SMN1; SMN2HDAC3HDAC7 | |
| SCHEMBL12035399 | 1.00 | HDAC4 (0.58) | HDAC4HDAC1SMN1; SMN2HDAC3HDAC7 | |
| SCHEMBL4320879 | 1.00 | HDAC4 (0.58) | HDAC4HDAC1SMN1; SMN2HDAC3HDAC7 | |
| SCHEMBL4320872 | 1.00 | HDAC4 (0.58) | HDAC4HDAC1SMN1; SMN2HDAC3HDAC7 | |
| SCHEMBL17867032 | 0.96 | HDAC4 (0.55) | HDAC4HDAC1SMN1; SMN2HDAC3HDAC7 | |
| SCHEMBL30423206 | 0.96 | HDAC1 (0.57) | HDAC4HDAC1SMN1; SMN2HDAC3HDAC7 | |
| SCHEMBL24614249 | 0.94 | HDAC4 (0.64) | HDAC4HDAC1HDAC3HDAC7HDAC2 | |
| SCHEMBL17866704 | 0.90 | HDAC4 (0.54) | HDAC4 | |
| SCHEMBL31237781 | 0.87 | HDAC4 (0.57) | HDAC4HDAC1HDAC3HDAC7HDAC2 | |
| SCHEMBL12035758 | 0.87 | HDAC4 (0.58) | HDAC4HDAC1SMN1; SMN2HDAC3HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190309289-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2019-10-10 | — | — | US | disclosed |
| US-10370654-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. (US) | 2019-08-06 | — | — | US | disclosed |
| US-20180320170-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2018-11-08 | — | — | US | disclosed |
| US-9944925-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. | 2018-04-17 | — | — | US | disclosed |
| US-20160186168-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2016-06-30 | — | — | US | disclosed |