Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.74 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.47 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CDC25A | P30304 | 2/20 | 0.34 |
| ▸ | CDC25B | P30305 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29511057 | 1.00 | PTPN1 (0.74) | PTPN1GPBAR1SLC10A1NR1H4PLA2G2A | |
| SCHEMBL30010403 | 0.88 | PTPN1 (0.76) | PTPN1GPBAR1SLC10A1NR1H4PLA2G2A | |
| SCHEMBL27936143 | 0.88 | PTPN1 (0.71) | PTPN1GPBAR1SLC10A1NR1H4PLA2G2A | |
| SCHEMBL4646248 | 0.88 | PTPN1 (0.76) | PTPN1GPBAR1SLC10A1NR1H4PLA2G2A | |
| SCHEMBL29352096 | 0.88 | PTPN1 (0.67) | PTPN1GPBAR1SLC10A1NR1H4PLA2G2A | |
| SCHEMBL17866708 | 0.86 | PTPN1 (0.62) | PTPN1GPBAR1SLC10A1NR1H4PLA2G2A | |
| Tetrahydroxybacteriohopane SCHEMBL7896032 | 0.85 | PTPN1 (0.61) | PTPN1GPBAR1SLC10A1NR1H4PLA2G2A | |
| SCHEMBL160601 | 0.85 | PTPN1 (1.00) | PTPN1GPBAR1SLC10A1NR1H4PRKCD | |
| SCHEMBL8068676 | 0.85 | PTPN1 (1.00) | PTPN1GPBAR1SLC10A1NR1H4PRKCD | |
| SCHEMBL18730236 | 0.84 | PTPN1 (0.69) | PTPN1GPBAR1SLC10A1NR1H4PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190309289-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2019-10-10 | — | — | US | disclosed |
| US-10370654-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. (US) | 2019-08-06 | — | — | US | disclosed |
| US-20180320170-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2018-11-08 | — | — | US | disclosed |
| US-9944925-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. | 2018-04-17 | — | — | US | disclosed |
| CN-106109585-A | Prevent and treat the pharmaceutical composition of breast carcinoma | 济南星懿医药技术有限公司 | 2016-11-16 | — | — | CN | disclosed |
| CN-106038832-A | Drug compound for treating breast cancer and preparation method thereof | 济南星懿医药技术有限公司 | 2016-10-26 | — | — | CN | disclosed |
| CN-106038633-A | Pharmaceutical composition capable of treating breast cancer | 济南星懿医药技术有限公司 | 2016-10-26 | — | — | CN | disclosed |
| CN-106038637-A | Pharmaceutical composition for treating breast cancer | 济南星懿医药技术有限公司 | 2016-10-26 | — | — | CN | disclosed |
| CN-105998087-A | Medicine composition for treating carcinoma of urinary bladder and preparation method thereof | 济南星懿医药技术有限公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-105998161-A | Pharmaceutical composition for preventing and treating breast cancer | 济南星懿医药技术有限公司 | 2016-10-12 | — | — | CN | disclosed |
| US-20160186168-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2016-06-30 | — | — | US | disclosed |