SCHEMBL17867317

SCHEMBL17867317

CC(NN=[SH2]=O)C(=O)N[C@@H](C)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ MME P08473 6/20 0.41
▸ ACE P12821 4/20 0.41
▸ CPA1 P15085 1/20 0.41
▸ ACE2 Q9BYF1 1/20 0.41
▸ LTA4H P09960 4/20 0.34
▸ RAB9A P51151 1/20 0.33
▸ LMNA P02545 1/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ ANPEP P15144 1/20 0.32
▸ ECE1 P42892 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16569260 0.72 MME (0.40) MMEACECPA1ACE2LTA4H
SCHEMBL12890745 0.70 MME (0.48) MMEACECPA1ACE2LTA4H
SCHEMBL13165106 0.70 MME (0.48) MMEACECPA1ACE2LTA4H
SCHEMBL12890774 0.70 MME (0.48) MMEACECPA1ACE2LTA4H
SCHEMBL15080628 0.70 MME (0.48) MMEACECPA1ACE2LTA4H
SCHEMBL23142762 0.70 MME (0.48) MMEACECPA1ACE2LTA4H
SCHEMBL18098146 0.70 MME (0.48) MMEACECPA1ACE2LTA4H
SCHEMBL15307782 0.70 MME (0.48) MMEACECPA1ACE2LTA4H
SCHEMBL13598642 0.70 MME (0.48) MMEACECPA1ACE2LTA4H
SCHEMBL9652457 0.69 MME (0.52) MMEACECPA1ACE2LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 — — US disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 — — US disclosed
US-20180320170-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2018-11-08 — — US disclosed
US-9944925-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. 2018-04-17 — — US disclosed
US-20160186168-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2016-06-30 — — US disclosed
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