SCHEMBL17867367

SCHEMBL17867367

Cc1cc(O)cc2c1C(=O)c1c(O)cc(O)cc1C2=O

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.73
ELANE P08246 4/20 0.73
ALDH1A1 P00352 4/20 0.73
MEN1 O00255 4/20 0.73
KMT2A Q03164 4/20 0.73
CYP3A4 P08684 3/20 0.73
MAPK1 P28482 3/20 0.73
TDP1 Q9NUW8 3/20 0.73
POLB P06746 2/20 0.73
APEX1 P27695 2/20 0.73
ALOX15 P16050 2/20 0.73
ESR1 P03372 2/20 0.73
ESR2 Q92731 2/20 0.73
TSHR P16473 2/20 0.73
NPC1 O15118 1/20 0.73
PTP4A3 O75365 1/20 0.73
GMNN O75496 1/20 0.73
LMNA P02545 1/20 0.73
TP53 P04637 1/20 0.73
CYP1A1 P04798 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30800495 1.00 MAPT (0.73) MAPTELANEALDH1A1MEN1KMT2A
SCHEMBL29390162 0.88 ESR1 (0.77) MAPTELANEALDH1A1MEN1KMT2A
SCHEMBL5968219 0.88 ESR1 (0.77) MAPTELANEALDH1A1MEN1KMT2A
SCHEMBL30505262 0.87 ELANE (0.71) MAPTELANEALDH1A1MEN1KMT2A
Emodin SCHEMBL29480997 0.85 ELANE (1.00) MAPTELANEALDH1A1MEN1KMT2A
Emodin SCHEMBL29630363 0.85 ELANE (1.00) MAPTELANEALDH1A1MEN1KMT2A
Emodin SCHEMBL29359841 0.85 ELANE (1.00) MAPTELANEALDH1A1MEN1KMT2A
Emodin SCHEMBL177689 0.85 ELANE (1.00) MAPTELANEALDH1A1MEN1KMT2A
SCHEMBL16432715 0.84 ELANE (0.67) MAPTELANEALDH1A1MEN1KMT2A
SCHEMBL29596416 0.84 ELANE (0.67) MAPTELANEALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117599026-A Application of deoxyerythrocin in preparation of drug for inhibiting drug-resistant staphylococcus aureus activity and cosmetics 上海致臻志臣科技有限公司 2024-02-27 CN disclosed
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 US disclosed
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 US disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 US disclosed
US-20180320170-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2018-11-08 US disclosed
US-9944925-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. 2018-04-17 US disclosed
US-20160186168-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2016-06-30 US disclosed