SCHEMBL17867643

SCHEMBL17867643

CC1(C)c2cc(-c3ccccc3-c3ccccc3)ccc2-c2cncnc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NCOA1 Q15788 1/20 0.40
▸ NCOA3 Q9Y6Q9 1/20 0.40
▸ MAPK9 P45984 1/20 0.37
▸ MAPK10 P53779 1/20 0.37
▸ CYP1A2 P05177 7/20 0.37
▸ CYP3A4 P08684 7/20 0.37
▸ CYP2D6 P10635 7/20 0.37
▸ CLK4 Q9HAZ1 3/20 0.37
▸ KDM4E B2RXH2 2/20 0.37
▸ ALOX5AP P20292 2/20 0.36
▸ FEN1 P39748 2/20 0.36
▸ RARB P10826 1/20 0.36
▸ RARG P13631 1/20 0.36
▸ RXRA P19793 1/20 0.36
▸ CYP2C19 P33261 6/20 0.36
▸ MAPK1 P28482 4/20 0.36
▸ HSD17B10 Q99714 4/20 0.36
▸ KMT2A Q03164 2/20 0.36
▸ MEN1 O00255 1/20 0.36
▸ ALDH1A1 P00352 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17867644 0.81 CYP3A4 (0.39) MAPK9MAPK10CYP1A2CYP3A4CYP2D6
SCHEMBL17867637 0.76 PDK2 (0.33) CLK4PDK2
SCHEMBL17886474 0.74 CYP1A2 (0.33) MAPK9MAPK10CYP1A2CYP3A4CYP2D6
SCHEMBL14508212 0.73 RARB (0.41) CLK4KDM4ERARBRARGRXRA
SCHEMBL14508289 0.72 PDK2 (0.41) RARBRARGRXRAKMT2AMEN1
SCHEMBL14508224 0.72 PDK2 (0.52) CYP1A2CYP2D6KDM4ERARBRARG
SCHEMBL14508215 0.72 PDK2 (0.41) CLK4RARBRARGRXRAKMT2A
SCHEMBL14508203 0.72 PDK2 (0.52) CYP1A2CYP2D6KDM4ERARBRARG
SCHEMBL9975003 0.72 ATM (0.41) ALOX5APFEN1PDK2BACE1
SCHEMBL29385477 0.72 PDK2 (0.46) RARBRARGRXRAPDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3040395-B1 ORGANIC MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME LUMINESCENCE TECH CORP (TW) 2017-10-18 — — EP disclosed
EP-3040395-B1 ORGANIC MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME LUMINESCENCE TECH CORP (TW) 2017-10-18 — — EP disclosed
US-9793493-B2 Organic material and organic electroluminescent device using the same LUMINESCENCE TECHNOLOGY CORP. (TW) 2017-10-17 — — US disclosed
US-9793493-B2 Organic material and organic electroluminescent device using the same LUMINESCENCE TECHNOLOGY CORP. (TW) 2017-10-17 — — US disclosed
US-9793493-B2 Organic material and organic electroluminescent device using the same LUMINESCENCE TECHNOLOGY CORP. (TW) 2017-10-17 — — US disclosed
EP-3040395-A1 ORGANIC MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME Luminescence Technology Corp. (TW) 2016-07-06 — — EP disclosed
US-20160190472-A1 ORGANIC MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORP. 2016-06-30 — — US disclosed
US-20160190472-A1 ORGANIC MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORP. 2016-06-30 — — US disclosed
US-20160190472-A1 ORGANIC MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORP. 2016-06-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160190472-A1 ORGANIC MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME EBPL, OXA1L, HBS1L NCOA1 2078/4885NCOA3 2744/4885MAPK9 1088/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback