SCHEMBL17867716

SCHEMBL17867716

O=CC1(c2ccc(O)c(O)c2)Oc2cc(O)cc(O)c2CC1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 5/20 0.43
KDM4E B2RXH2 5/20 0.43
HSD17B10 Q99714 4/20 0.43
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
GAA P10253 3/20 0.43
PKM P14618 3/20 0.43
MAPT P10636 3/20 0.43
RECQL P46063 3/20 0.43
ALOX15 P16050 3/20 0.43
CYP3A4 P08684 3/20 0.43
ALDH1A1 P00352 2/20 0.43
APEX1 P27695 2/20 0.43
ALPL P05186 2/20 0.43
POLB P06746 2/20 0.43
PTGS1 P23219 2/20 0.43
PTGS2 P35354 2/20 0.43
APP P05067 2/20 0.43
SNCA P37840 2/20 0.43
RAD52 P43351 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5466949 0.80 BACE1 (0.41) BACE1KDM4EHSD17B10MEN1KMT2A
SCHEMBL11206311 0.80 BACE1 (0.43) BACE1KDM4EHSD17B10MEN1KMT2A
SCHEMBL6262620 0.79 BACE1 (0.46) BACE1KDM4EHSD17B10MEN1KMT2A
SCHEMBL6262786 0.79 BACE1 (0.46) BACE1KDM4EHSD17B10MEN1KMT2A
SCHEMBL20169853 0.79 BACE1 (0.46) BACE1KDM4EHSD17B10MEN1KMT2A
SCHEMBL14392073 0.79 BACE1 (0.46) BACE1KDM4EHSD17B10MEN1KMT2A
SCHEMBL6262789 0.79 BACE1 (0.46) BACE1KDM4EHSD17B10MEN1KMT2A
SCHEMBL4728425 0.79 BACE1 (0.46) BACE1KDM4EHSD17B10MEN1KMT2A
SCHEMBL1578287 0.78 BACE1 (0.43) BACE1KDM4EHSD17B10MEN1KMT2A
SCHEMBL6213448 0.77 BACE1 (0.44) BACE1KDM4EHSD17B10MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10004679-B2 Compositions of Amorphophallus konjac and methods for their use in skin care Vidya Herbs, Inc. (US) 2018-06-26 US disclosed
EP-3040104-A1 COMPOSITIONS OF AMORPHOPHALLUS KONJAC EXTRACT AND METHODS FOR THEIR USE IN SKIN CARE Kodimule, Shyam Prasad (IN) 2016-07-06 EP disclosed
US-20160184218-A1 COMPOSITIONS OF AMORPHOPHALLUS KONJAC AND METHODS FOR THEIR USE IN SKIN CARE PRASAD KODIMULE (IN) 2016-06-30 US disclosed