SCHEMBL17874544

SCHEMBL17874544

Cc1ccc2c(c1)nc(N)c1ncc(CCc3ccc(OCCOCCOCCCC(F)(F)P(C)(=O)O)cc3C)cc12

nearest known ligand 0.84

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.84

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17874547 0.96 TLR7 (0.90) TLR7
SCHEMBL17874537 0.96 TLR7 (0.90) TLR7
SCHEMBL10310947 0.95 TLR7 (0.93) TLR7
SCHEMBL255327 0.91 TLR7 (1.00) TLR7
SCHEMBL30575420 0.91 TLR7 (1.00) TLR7
SCHEMBL30575441 0.91 TLR7 (1.00) TLR7
SCHEMBL255388 0.91 TLR7 (1.00) TLR7
SCHEMBL1527522 0.91 TLR7 (1.00) TLR7
SCHEMBL30575430 0.91 TLR7 (1.00) TLR7
SCHEMBL12288554 0.89 TLR7 (0.89) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9375471-B2 Adjuvanted formulations of booster vaccines GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2016-06-28 US disclosed