Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.43 |
| ▸ | UBE2N | P61088 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25779662 | 0.89 | HPGD (0.73) | HPGDLMNACYP3A4TSHRMAPK1 | |
| SCHEMBL25448567 | 0.88 | HPGD (0.68) | HPGDLMNACYP3A4TSHRMAPK1 | |
| SCHEMBL17897166 | 0.83 | HPGD (1.00) | HPGDLMNANPC1RAB9AALOX5 | |
| SCHEMBL13889056 | 0.83 | HPGD (0.76) | HPGDLMNACYP3A4TSHRMAPK1 | |
| SCHEMBL15314137 | 0.81 | HPGD (0.72) | HPGDLMNACYP3A4TSHRMAPK1 | |
| SCHEMBL16748053 | 0.81 | HPGD (0.72) | HPGDLMNACYP3A4TSHRMAPK1 | |
| SCHEMBL13594462 | 0.79 | HPGD (0.69) | HPGDLMNACYP3A4TSHRMAPK1 | |
| SCHEMBL18325693 | 0.77 | HPGD (0.66) | HPGDLMNACYP3A4TSHRMAPK1 | |
| SCHEMBL7372064 | 0.75 | HPGD (0.64) | HPGDLMNACYP3A4TSHRMAPK1 | |
| SCHEMBL17171336 | 0.75 | HPGD (0.64) | HPGDLMNACYP3A4TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9376381-B2 | High penetration prodrug compositions of peptides and peptide-related compounds | TECHFIELDS PHARMA CO., LTD. (CN) | 2016-06-28 | — | — | US | disclosed |