Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | CTSV | O60911 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | PARP1 | P09874 | 2/20 | 0.48 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.47 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.47 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16138106 | 0.87 | DAO (0.53) | CA12CA9ALOX5L3MBTL1CTSV | |
| SCHEMBL8834687 | 0.83 | KDM4E (0.53) | CA12CA9L3MBTL1PARP1GRIA1 | |
| SCHEMBL10998454 | 0.78 | CA12 (0.69) | CA12CA9L3MBTL1CTSVCTSL | |
| SCHEMBL16007675 | 0.76 | CA12 (0.58) | CA12CA9L3MBTL1CTSVCTSL | |
| Tert-Butyl Formate SCHEMBL28043656 | 0.76 | DAO (0.42) | CA12CA9ALOX5L3MBTL1CTSV | |
| SCHEMBL31482838 | 0.74 | MAPT (0.53) | CA12CA9L3MBTL1PARP1GRIA1 | |
| SCHEMBL31482835 | 0.74 | MAPT (0.53) | CA12CA9L3MBTL1PARP1GRIA1 | |
| SCHEMBL3648969 | 0.74 | MAPT (0.53) | CA12CA9L3MBTL1PARP1GRIA1 | |
| SCHEMBL7431126 | 0.72 | CA12 (0.64) | CA12CA9L3MBTL1CTSVCTSL | |
| SCHEMBL17434518 | 0.72 | CA12 (0.64) | CA12CA9L3MBTL1CTSVCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2710013-B1 | NOVEL COMPOUNDS AS DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2016-06-29 | — | — | EP | disclosed |